Overview

This text is aimed at defining the current concepts that define trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It will serve as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader will have full understanding of the tests that are used to study trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications are reviewed in detail. Trauma Induced Coagulopathy will also be a valuable source for quick reference to the clinician that is faced with specific clinical challenges when managing coagulopathy.

Full Product Details

Author:   Eduardo Gonzalez ,  Hunter B. Moore ,  Ernest E. Moore, MD
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2016
Dimensions:   Width: 17.80cm , Height: 3.30cm , Length: 25.40cm
Weight:   1.193kg
ISBN:  

9783319803227

ISBN 10:   3319803220
Pages:   601
Publication Date:   30 April 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Trauma Induced Coagulopathy Eduardo Gonzalez, Hunter B. Moore, Ernest E. Moore   Table of Contents   ·         Foreword Kenneth Mann   ·         Preface Ernest E. Moore, Hunter B. Moore, Eduardo Gonzalez   ·         Introduction: Historical Perspective: History of Trauma Induced Coagulopathy Ernest E. Moore, Eduardo Gonzalez, Hunter B. Moore     Part 1: Physiology of Hemostasis Chapter 1: Cell-Mediated Hemostasis Maureane Hoffman   Chapter 2: Antithrombin Contributions to Physiological Hemostasis and Thrombosis Prevention, and its Dysregulation in Trauma and TIC Susan C. Bock   Chapter 3: Physiology of Hemostasis: Plasmin-antiplasmin system Nicola J Mutch, Nuala A Booth     Part 2: Pathogenesis of Trauma Induced Coagulopathy Chapter 4: Thrombin Formation Shekhar Kumar, Sriram Krishnaswamy   Chapter 5: Fibrinogen Eduardo Gonzalez, Ernest E. Moore, Hunter B. Moore   Chapter 6: Activated Protein C Mitchell Jay Cohen, Benjamin M. Howard   Chapter 7: Pathogenesis of Trauma Induced Coagulopathy: The Endothelium Pär I. Johansson, Sisse R. Ostrowski   Chapter 8: Platelets Scott L. Diamond   Chapter 9: Fibrinolysis Hunter B. Moore, Ernest E. Moore, Eduardo Gonzalez   Chapter 10: Neutrophils, Inflammation and Innate Immunity in Trauma-Induced Coagulopathy Christopher D. Barrett, Michael B. Yaffe   Chapter 11: DAMPs: Damage-Associated Molecular Pattern Molecules in Hemostasis Charles T. Esmon  < Chapter 12: The Complement System and Coagulation Narcis I. Popescu, Florea Lupu   Chapter 13: Disseminated Intravascular Coagulation Satoshi Gando     Part 3: Coagulation Assessment in Trauma Induced Coagulopathy Chapter 14: Prothrombin and Partial Thromboplastin Time Ruchika Goel, Paul M Ness   Chapter 15: Fibrinogen Assays Christoph J. Schlimp, Herbert Schöchl             Chapter 16: Platelet Aggregometry Taizo Nakano, Jorge Di Paola   Chapter 17: Thrombelastography Eduardo Gonzalez, Ernest E. Moore, Hunter B. Moore   Chapter 18: Rotational Thromboelastometry (ROTEM®) Klaus Görlinger, Daniel Dirkmann, Alexander A. Hanke     Part 4: Management of Trauma Induced Coagulopathy Chapter 19: Red Blood Cell: Manufacture, Storage, and Transfusion F. Bernadette West, Marguerite R. Kelher, Christopher C. Silliman   Chapter 20: Plasma Transfusion Ryan A. Lawless, John B. Holcomb   Chapter 21: Cryoprecipitate Transfusion Jeannie L. Callum, Bartolomeu Nascimento   Chapter 22: The Evolving Role of Platelets in Trauma Care Andrew P. Cap, Todd Getz, Philip Spinella, Heather Pidcoke   Chapter 23: Massive Transfusion Protocols Alexis M. Moren, Samantha J. Underwood, Martin A. Schreiber   Chapter 24: Fibrinogen and Clotting Factor Replacement Massimo Franchini   Chapter 25: Anti-Fibrinolytics Dominik F. Draxler, Robert L. Medcalf, Russell L. Gruen     Part 5: Post-injury Hypercoagulability Chapter 26: Venous Thromboembolism Steven R. Shackford, C. Beth Sise   Chapter 27: Congenital and Acquired Hypercoagulable States Joseph Emmerich     Part 6: Organ-specific Coagulopathy Chapter 28: Coagulopathy in Traumatic Brain Injury (TBI) Marc Maegele   Chapter 29: Liver Disease Shahzaib Ahmad, Beverly J Hunt   Chapter 30: Hemostatic Abnormalities in Renal Disease Michael P. Chapman, Anirban Banerjee, Ernest E. Moore     Part 7: Trauma Induced Coagulopathy in Special Populations Chapter 31: Pediatrics Robert I. Parker   Philippe de Moerloose, T. Marchetti, A. Casini   Chapter 33: Management of Chronically Anticoagulated Patients Jerrold H. Levy     Part 8: Research of Trauma Induced Coagulopathy Chapter 34: Animal Models Ted Bambakidis, Martin Sillesen, Hasan B. Alam   Chapter 35: Mathematical Models of Hemostasis Keith B. Neeves, Karin Leiderman    

Reviews

This is a collection of reviews describing the most important early complication of injury. ... Senior trainees, basic scientists seeking clinical connection, and surgeons, particularly those in academic trauma practice, are an appropriate audience for this book from international authorities. ... This is an important contribution that will guide senior clinicians and basic scientists seeking to better define this important clinical problem. The editors have been careful to assemble rigorous reviews that indicate the strengths and limitations of contemporary evidence. (David J. Dries, Doody's Book Reviews, August, 2016) This is a collection of reviews describing the most important early complication of injury. Senior trainees, basic scientists seeking clinical connection, and surgeons, particularly those in academic trauma practice, are an appropriate audience for this book from international authorities. This is an important contribution that will guide senior clinicians and basic scientists seeking to better define this important clinical problem. The editors have been careful to assemble rigorous reviews that indicate the strengths and limitations of contemporary evidence. (David J. Dries, Doody's Book Reviews, August, 2016)

Author Information

Ernest E. Moore, MD is Editor, Journal of Trauma and Acute Care Surgery (LWW)

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