Thyroid Hormone Receptors: Methods and Protocols
Author:   Aria Baniahmad
Publisher:   Humana Press Inc.
Edition:   2002 ed.
Volume:   202
ISBN:  

9780896039957


Pages:   223
Publication Date:   04 June 2002
Format:   Hardback
Availability:   Out of stock   Availability explained
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Thyroid Hormone Receptors: Methods and Protocols


Overview

A panel of outstanding investigators surveys and explains the major cutting-edge methods used in thryroid receptor (TR) research and explains their practical experimental details. Described in step-by-step detail to ensure robust experimental results, the techniques presented cover a wide variety of key areas, including TR in development and knockout (mouse and Xenopus), transcriptional regulation by TRs in both cell free systems and in living cells, and TR mutant analysis of patients. Additional methods provide powerful tools for the isolation of TR-regulated protein complexes, for studying the oncogene v-Erba in blood cell differentiation, and for target gene analysis in the brain. Microarray chip methods are also presented for analyzing the organs of transgenic mice to identify target genes in the liver.

Full Product Details

Author:   Aria Baniahmad
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   2002 ed.
Volume:   202
Dimensions:   Width: 15.50cm , Height: 2.10cm , Length: 23.50cm
Weight:   0.567kg
ISBN:  

9780896039957


ISBN 10:   0896039951
Pages:   223
Publication Date:   04 June 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

to Thyroid Hormone Receptors.- Null Mutant Mice for Thyroid Hormone Receptors.- Transgenic Targeting of a Dominant Negative Corepressor to Liver and Analyses by cDNA Microarray.- The Role of Thyroid Hormone Receptors in the Heart.- Analysis of Thyroid Hormone-Dependent Genes in the Brain by In Situ Hybridization.- The v-erbA Oncogene.- Gene Regulation by Thyroid Hormone Receptors.- Molecular Analysis of Human Resistance to Thyroid Hormone Syndrome.- Function of Thyroid Hormone Receptors During Amphibian Development.- Transcriptional Regulation by Thyroid Hormone Receptor in Chromatin.- Gene Activation by Thyroid Hormone Receptor In Vitro and Purification of the TRAP Coactivator Complex.

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