Overview
This book is a collection of protocols, to provide novel techniques for the study of the biology of T lymphocytes. The methods described in this book do not cover all of the techniques currently used to study T cell-mediated immune responses for the simple reason that T cell immunology is probably the immunological discipline which can be investigated with the widest variety of approaches. Thechoiceofchapterswasmadetakingintoaccounttwopoints:First,manyofthe techniquesthathavebeen usedfor sometimehave beenupgraded duringthe pastfew years given the greater availability of a variety of products (i.e. cytokines, chemokines, monoclonal antibodies), of refined technical devices (i.e. novel cell culture and cell analysis equipments), and the development of novel instrumentation (i.e. multipa- metric flow cytometers, confocal microscopes). Therefore, in several chapters ‘‘old techniques’’, which remain fundamental to T cell immunology, are described in their ‘‘modern’’ versions. Secondly, the technical advancement has generated the possibility to establish novel assays to investigate T cell physiology. This is reflected in the chapters which describe the protocols that allow use of these modern approaches. The preparation of this book has required participation of several scientists, all leading experts in their respective fields. Without their enthusiastic participation, this work would not have been possible. Therefore, I thank all authors for their contri- tionsandacceptallcriticismformissingparts,orinformationordetails,forwhichonly I am responsible. I hope these protocols will be useful for young investigators who approach for the first time the complex field of immunology and for those more experienced scientists who look for concise and efficaciousdescriptions of novel methods.
Full Product Details
Author: Gennaro De Libero
Publisher: Humana Press Inc.
Imprint: Humana Press Inc.
Edition: 2nd ed. 2009
Volume: 514
Dimensions:
Width: 19.30cm
, Height: 1.50cm
, Length: 26.00cm
Weight: 0.661kg
ISBN: 9781588295873
ISBN 10: 1588295877
Pages: 166
Publication Date: 10 December 2008
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Active
Availability: In Print
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.
Reviews
From the reviews of the second edition: A great collection of protocols, some totally new and some upgraded ... to study the biology of this fascinating cell is wellcome by the scientific community. ... Thanks to the generation of ... PFC, is now at the hands of those scientists that want to advance our understanding of T cells biology. ... the book will be of enourmous help both to beginners and to experienced scientists is well underlining the esprit of the book, as I showed with the three examples illustrated. (CarloAlberto Redi, European Journal of Histochemistry, October, 2009)
From the reviews of the second edition: A great collection of protocols, some totally new and some upgraded ! to study the biology of this fascinating cell is wellcome by the scientific community. ! Thanks to the generation of ! PFC, is now at the hands of those scientists that want to advance our understanding of T cells biology. ! the book will be of enourmous help both to beginners and to experienced scientists is well underlining the esprit of the book, as I showed with the three examples illustrated. (CarloAlberto Redi, European Journal of Histochemistry, October, 2009)
