Overview

Since prehistoric times, humans have consumed probiotic foods and prebiotic components of food, developing them through modification in substrates, processes, and technology. In the current era, health-conscious consumers demand functional food with health-promoting activity. Synbiotics positively affect the gut microbiota population and, therefore, improve human health and well-being. As the demand for healthy food increases globally, manufacturers are searching for new possibilities to occupy a share in the rapidly evolving food market. This book covers synbiotics and advances in food microbiology, its concepts, trends, and safety aspects. It covers the utilization of microbes in different types of foods, encompassing the background, principles, classification, applications, equipment, effect on foods, legislative issues, technology implementation, constraints, and food and human safety concerns, making it a comprehensive resource for academics and industry professionals alike.

Full Product Details

Author:   Anil Panghal (Chaudhary Charan Singh Haryana Agricultural University, India) ,  Namita Singh (Guru Jambheshwar University of Science and Technology, India) ,  R. C. Kuhad (Shree Guru Gobind Singh Tricentenary University, India) ,  Mandeep Kumar (Guru Jambheshwar University of Science and Technology, India)
Publisher:   John Wiley & Sons Inc
Imprint:   Wiley-Scrivener
ISBN:  

9781394269051

ISBN 10:   1394269056
Pages:   944
Publication Date:   26 April 2026
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Forthcoming
Availability:   Out of stock  

Table of Contents

Synbiotics, Volume 1: Revolutionizing Health and Disease Management Preface xv 1 The New Frontier in Healthy Living: Synbiotic Drinks Combining Probiotics and Prebiotics 1 Taruna Sheoran, Mandeep Kumar, Navnidhi Chikkara and Namita Singh 2 Synbiotics: Production, Applications, and Health Promotion 37 Nidhi Gupta and Manjula Gautam 2.1 Introduction 38 2.2 Synbiotic Formulation 39 2.3 Applications 41 2.4 Synbiotics in the Prevention and Management of Chronic Illnesses 47 2.5 Impact of Synbiotics on Health Promotion 52 2.6 Conclusion 53 2.7 Perspectives for the Future 53 3 Understanding the Role of Multi-Strain Probiotics in Improving Consumer Health 65 Samridhi Pushkarna, Kajal Gaba, Shruti Kharod, Parveen Malhotra, Amita Suneja Dang and Pooja Suneja 3.1 Introduction 65 3.2 Mechanism of Action 67 3.3 Benefits of Multi-Strain Probiotics 69 3.4 Applications of Multi-Strain Probiotics 71 3.5 Conclusion 83 4 Co-Encapsulated Synbiotics for Improved Human Health 91 Bharti Datten, Nikita Jangra and Pooja Gulati 4.1 Introduction 92 4.2 Co-Encapsulated Synbiotics 93 4.3 Carriers Used for Co-Encapsulation 96 4.4 Microencapsulation 98 4.5 Nanoencapsulation 102 4.6 Encapsulated Synbiotics in Promoting Gut Health 105 4.7 Side Effects Associated with Encapsulated Synbiotics In Vivo 106 4.8 Concluding Remarks 107 5 Unveiling the Role of Synbiotics in Infant Well-Being 115 Parul Chugh, Swati Misra, Shailendra Raghuwanshi and Mahesh S. Dhar 6 Probiotics and Chronic Diseases 137 Mrinali Hakim Kaul 6.1 Chronic Diseases 139 6.2 Function of Gut Microbiota in Chronic Diseases 140 6.3 Probiotics 141 6.4 Probiotics in Chronic Diseases 144 6.5 Future of Probiotics in Chronic Disease 154 6.6 Conclusion 155 7 Exploring the Connection Between Probiotics and Chronic Diseases 169 Kajal Gaba, Samridhi Pushkarna, Shruti Kharod, Parveen Malhotra, Pooja Suneja and Amita Suneja Dang 7.1 Introduction 170 7.2 Mechanism of Action of Probiotics 171 7.3 Probiotics in Chronic Diseases Management 172 7.4 Conclusion 184 8 Probiotics and Chronic Disease: A Microbial Approach to Prevention and Management 189 Akriti Thakur, Sonia Morya and Arno Neumann 8.1 Introduction 190 8.2 Chronic Diseases and Their Impact 196 8.3 The Gut Microbiome and Chronic Diseases 199 8.4 Probiotics and Other Living Microorganism Biotherapies 206 8.5 Mechanism of Action of Probiotics 209 8.6 Clinical Studies and Results 210 8.7 Conclusion 211 9 Exploring the Triad: Prebiotics, Probiotics, and Synbiotics in Promoting Bone Health 223 Lakhvinder Kaur 9.1 Introduction 224 9.2 Importance of Prebiotics and Probiotics 226 9.3 Prebiotics in Human Health 229 9.4 Probiotics in Human Health 233 9.5 Synbiotics in Human Health 234 9.6 Impact of Probiotics on Bone Health 234 9.7 The Role of Probiotics in Inflammatory Homeostasis 235 9.8 Studies Emphasizing the Importance of Probiotics for Bone Health 237 9.9 The Relationship Between Prebiotics and Bone Health 239 9.10 Other Therapeutic Advantages of Prebiotics 241 9.11 Summary 241 10 Probiotics and Prebiotics in Oral Health 251 Anamika Chauhan and Simple Sharma 10.1 Introduction 252 10.2 Composition of Oral Microbiota 254 10.3 Probiotics in Oral Health 255 10.4 Prebiotics in Oral Health 258 10.5 Oral Conditions and Probiotics/Prebiotics 262 10.6 Prebiotics and Probiotics in Commercial Oral Health Products 268 10.7 Current Uses of Probiotics and Prebiotics 269 10.8 Safety and Regulations 269 10.9 Implications of the Potential of Probiotics and Prebiotics in Promoting Oral Health 279 10.10 Conclusion 280 11 Synbiotics and the Immune System 291 Mrinali Hakim Kaul Introduction 291 11.1 Historical Overview 293 11.2 Gut Microbiome and Immunity 294 11.3 Synbiotics 296 11.4 Impact of Synbiotics on the Immune System 300 11.5 Role in Diseases 307 11.6 Future Directions 313 11.7 Conclusion 313 12 Probiotics and Prebiotics for the Immune System 323 Prasann Kumar and Joginder Singh 12.1 Introduction 324 12.2 Understanding Synbiotics 328 12.3 Safety Assessment of Probiotics 331 12.4 Toxicity Considerations of Prebiotics: An Overview of Prebiotic Safety 339 12.5 Interactions and Synergy in Synbiotics 347 12.6 Immunomodulatory Effects and Host Response 351 12.7 Long-Term Safety and Health Outcomes 354 12.8 Safety Considerations in Special Populations 357 12.9 Regulatory Landscape and Labeling Requirements 360 12.10 Conclusion 363 13 Synbiotics for Promoting Health 371 Ankita Sharma and Madhvi Awasthi 13.1 Synbiotics and Hormonal Regulation 375 13.2 Synbiotics and Thyroid Function 378 13.3 Synbiotics and Immunity 379 13.4 Synbiotics and Renal Function 380 13.5 Synbiotics and Skeletal System 381 13.6 Synbiotic and Cardiovascular System 382 13.7 Synbiotic and Respiratory Tract 383 13.8 Synbiotic and Gastrointestinal Tract 384 13.9 Synbiotic and Liver 385 14 Synbiotics in Cytotoxicity 393 Shruti Kharod, Samridhi Pushkarna, Kajal Gaba, Anil Kumar, Pooja Suneja and Amita Suneja Dang 14.1 Introduction 393 14.2 Synbiotics 394 14.3 Mechanisms of Synbiotic-Mediated Cytotoxicity Modulation 396 14.4 Synbiotics and Cytotoxicity in Specific Disease States 398 14.5 Future Directions 416 4.6 Conclusion 418 15 Synbiotics—Safety and Toxicity Considerations 429 Manjula Gautam and Nidhi Gupta 15.1 Introduction 430 15.2 Safety Evaluation 442 15.3 Synbiotic Safety Measures 443 15.4 Regulatory Considerations 445 15.5 Safety Assessment of Probiotics 445 15.6 Safety Evaluation of Prebiotics 447 15.7 Toxicity Investigations of Synbiotics 448 15.8 Management of Chemotherapy-Related Symptoms with Synbiotic Therapy 449 15.9 Concluding Remarks and Future Directions 454 References 455 Synbiotics, Volume 2: Harnessing Probiotics and Prebiotics for Nutrition Preface xiii 16 Commercially Exploitable Probiotic Microorganisms for Humans 467 Taruna Sheoran, Anil Panghal and Namita Singh 17 Probiotic Microorganism 491 Gopika S. Pillai and Sonia Morya 17.1 Introduction 491 17.2 Diversity and Types of Probiotic Microorganisms 495 17.3 Sources of Probiotics 514 17.4 Dietary Supplements 517 17.5 Health Benefits and Applications 524 17.6 Future Applications and Emerging Research Areas 529 17.7 Conclusion 530 18 Mechanism of Action of Probiotics 547 S. Pooja, Vidya Niranjan, Anagha S. Setlur, Chandrashekar K. and Sinosh Skariyachan 18.1 Introduction 548 18.2 Overview of Probiotics—Need and Importance 549 18.3 Classification and Types of Probiotics 550 18.4 Major Types of Probiotic Microorganisms and Their Microbiological Aspects 551 18.5 Major Mechanism of Probiotics 554 18.6 Conclusion 576 18.7 Future Perspectives 576 19 Synbiotics in Nutrition 593 Enespa and Prem Chandra 19.1 Introduction 593 19.2 Antioxidant Properties of Synbiotics 598 19.3 Health Benefits and Therapeutic Potentials 604 19.4 Applications to Animal Health 613 19.5 Conclusions 618 20 Synbiotics in Nutrition: The Synergy of Probiotics and Prebiotics 631 Mounika P.A. Reddy and Manesh Muraleedharan 20.1 Overview of Probiotics and Prebiotics 632 20.2 Mechanism of Synbiotics 636 20.3 Dietary Sources of Synbiotics 642 20.4 The Significance of the Gut Microbiome in Human Health 644 20.5 Application of Synbiotics in Health Management 651 20.6 Progress and Prospects in Synbiotic-Based Nutrition Research 657 21 Microencapsulation in Synbiotics and Its Food Application 675 Yogesh Kumar and Swarnima Dey 21.1 Introduction 675 21.2 Role of Microorganisms in Synbiotics 679 21.3 Selection of Wall Material in Microencapsulatio of Synbiotics 680 21.4 Preparation of Microencapsulated Synbiotics 684 21.5 Application of Microencapsulated Synbiotics in Foods 692 21.6 Future Prospective in Microencapsulated Synbiotics 694 21.7 Conclusion 695 22 Microencapsulation of Synbiotics 701 Abishek Dinesh and Sonia Morya 22.1 Introduction 702 22.2 Microencapsulation of Synbiotics 703 22.3 Microencapsulation Methods 712 22.4 Applications of Microencapsulated Synbiotics in Food 720 22.5 Current Challenges 725 22.6 Future Prospects 726 22.7 Conclusion 727 23 Prebiotics Addition in Dairy Products 737 Semih Otles and Gozde Turkoz Bakirci 23.1 Introduction 737 23.2 Conceptual Framework (Prebiotics, Probiotics, Differences, Applications, Synbiotics) 738 23.3 Studies in the Literature Regarding the Use of Prebiotics in Dairy Products 745 23.4 Results and Recommendations 748 24 Synbiotic Usage in Children 753 Urvashi Mudgil, Permender Singh, Krishan Kumar and Vinita Bhankar 24.1 Synbiotics for Promoting Growth in Children 756 24.2 Effect of Synbiotics on Gi Issues in Children 757 24.3 Support to Immune System of Children 761 24.4 Role of Gut-Microbiota-Brain Axis in Children with Cerebral Palsy 765 24.5 Effect of Synbiotics on Cardiovascular Diseases in Children 766 24.6 Effect of Synbiotics on Uric Acid in Children 767 24.7 Conclusion 767 25 Role of Synbiotics in Infant Nutrition 777 Manju Tewari, Prerna Pande, Saloni Godiyal and Veena Pande 25.1 Infant Nutrition 777 25.2 Gut Microbiome in Infants 780 25.3 Synbiotics 780 25.4 Conclusions 793 26 Significance of Probiotics in the Context of Chronic Disease: Recent Revelations 805 Chandra Mohana. N., Narendra Kumar H. K., Kiran Kumar M.N. and Satish S. 27 Synbiotics: Safety and Toxicity Considerations 823 Prasann Kumar and Joginder Singh 27.1 Introduction 824 27.2 Understanding Synbiotics 826 27.3 Safety of Probiotics 831 27.4 Safety of Prebiotics 834 27.5 Interactions and Synergies 843 27.6 Toxicity Concerns 849 27.7 Assessing and Monitoring Safety 851 27.8 Future Directions and Challenges 854 27.9 Conclusion and Recommendations 856 28 Regulatory Framework for Use of Probiotics 863 Mahima Verma and Jasvir Singh 28.1 Introduction 864 28.2 Regulatory Framework for the Use of Probiotics in Food 864 28.3 Regulatory Framework for Use of Probiotics in Pharma 874 28.4 Regulatory Framework for Use of Probiotics in Animal Feed 878 28.5 Conclusions 879 Bibliography 880 Index 881

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Author Information

Anil Panghal, PhD is an Assistant Scientist in the Department of Processing and Food Engineering in the College of Agricultural Engineering and Technology at Chaudhary Charan Singh Haryana Agricultural University. He has published several research papers in reputed journals and chapters for international publishers. His areas of expertise include bioprocessing, manufacturing, food chemistry, food science and technology, and nutrition. Namita Singh, PhD is a Professor in the Department of Bio and Nano Technology at the Guru Jambheshwar University of Science and Technology with more than 22 years of experience. She has published 40 national and 60 international publications, one book, three manuals, and one patent. Her areas of expertise include microbial biotechnology, fermentation technology, environmental biotechnology, algal biotechnology, enzyme technology, and solid waste management. Ramesh Chander Kuhad, PhD is the Pro-Chancellor at Shree Guru Gobind Singh Tricentenary University with more than 35 years of experience. He has authored more than 200 publications, edited five books, and has four patents to his credit in different areas of crop by-product biotechnology. His research focuses on microbial ecology, bioprocess engineering and fermentation technology, and wastewater treatment. Mandeep Kumar is a research scholar in the Department of Bio and Nano Technology at the Guru Jambheshwar University of Science and Technology. He completed his postgraduate work in biochemistry at Kurukshetra University. His PhD thesis focuses on the development of vegetable-based probiotic drinks and the evaluation of their bioactivity.

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