Overview

This must-have cell signaling title will appeal to researchers across molecular biology, biochemistry, cell biology and genetics. The articles are written and edited by experts in the field and emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, the regulation of endoplasmic reticulum function, control of cell cycle progression and apoptosis and the modulation of the activities of mitochondria and other organelles.

Full Product Details

Author:   Ralph A. Bradshaw ,  Edward A. Dennis
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Dimensions:   Width: 21.60cm , Height: 2.50cm , Length: 27.60cm
Weight:   1.610kg
ISBN:  

9780123822130

ISBN 10:   0123822130
Pages:   550
Publication Date:   05 April 2011
Audience:   College/higher education ,  Postgraduate, Research & Scholarly
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

244 Nuclear Receptor Coactivators 245 Corepressors in Mediating Repression by Nuclear Receptors 246 Steroid Hormone Receptor Signaling 247 Role of COUP-TFII in Congenital Diaphragmatic Hernia 248 Nuclear Receptors in Drosophila melanogaster 249 JAK-STAT Signaling 250 FOXO Transcription Factors: Key Targets of the PI3K-Akt Pathway 251 The Multi-gene Family of Transcription Factor AP-1 252 NF-KB: a Key Integrator of Cell Signaling 253 Transcriptional Regulation via the cAMP Responsive Activator CREB 254 The NFAT Family: Structure, Regulation and Biological Functions 255 Ubiquitination/Proteasome 256 The SMADs 257 Complexity of Stress Signaling 258 Signal Transduction in the Escherichia coli SOS Response 259 Oxidative Stress and Free Radical Signal Transduction 260 Screening Approaches to Identify Genes Required for DNA Double-Strand Break 261 Radiation Responses in Drosophila 262 Double-strand Break Recognition and its Repair by Non-homologous End Joining 263 ATM-Mediated Signaling Defends the Integrity of the Genome 264 Signaling to the p53 Tumor Suppressor through Pathways 265 The p53 Master Regulator and Rules of Engagement with Target Sequences 266 Nuclear and Cytoplasmic Functions of Abl Tyrosine Kinase 267 Radiation-induced Cytoplasmic Signaling 268 The Heat-Shock Response and the Stress of Misfolded Proteins 269 Hypoxia-Mediated Signaling Pathways 270 Regulation of mRNA Turnover by Cellular Stress 271 Oncogenic Stress Responses 272 Ubiquitin and FANC Stress Responses 273 Stress and g -H2AX 274 Translational Control by Amino Acids and Energy 275 Translation Control and Insulin Signaling 276 ER and oxidative stress: Implications in disease 277 Regulation of mRNA Turnover 278 Signaling to Cytoplasmic Polyadenylation and Translation 279 Translational Control in Invertebrate Development 280 The Role of Alternative Splicing During the Cell Cycle and Programmed Cell Death 281 Signaling Pathways that Mediate Translational Control of Ribosome Recruitment 282 The SWI/SNF and RSC Nucleosome Remodeling Complexes 283 ISWI Chromatin Remodeling Complexes 284 The INO80 Chromatin Remodeling Complex 285 Histone Acetylation Complexes 286 Regulation of Histone Deacetylase Activities and Functions by Phosphorylation and 287 Histone Methylation: Chemically Inert But Chromatin Dynamic 288 Histone Phosphorylation: Chromatin Modifications 289 Histone Variants: Signaling or Structural Modules? 290 Silent Chromatin Formation and Regulation in the Yeast Saccharomyces cerevisiae 291 Gene Silencing and Chromatin Modification by Polycomb Complexes 292 Histone Ubiquitination 293 Chromatin-mediated Control of Gene Expression in Innate Immunity and Inflammation

Reviews

In order to keep researchers and students up to date on developments in the field, 55 articles were selected and reprinted from the 2008 second edition of the `Handbook of Cell Signaling' on the transcriptional regulation and the function of nuclei and other subcellular organelles in signaling activities. After an overview, they cover nuclear signaling in transcription, chromatic remodeling, and stress response; signaling to and from intracellular compartments; and cell cycle and cell death signaling. This is one of four volumes of such reprints, called the Cell Signaling Collection. --Reference and Research Book News

In order to keep researchers and students up to date on developments in the field, 55 articles were selected and reprinted from the 2008 second edition of the 'Handbook of Cell Signaling' on the transcriptional regulation and the function of nuclei and other subcellular organelles in signaling activities. After an overview, they cover nuclear signaling in transcription, chromatic remodeling, and stress response; signaling to and from intracellular compartments; and cell cycle and cell death signaling. This is one of four volumes of such reprints, called the Cell Signaling Collection. --Reference and Research Book News

Author Information

Ralph A. Bradshaw is Professor of Chemistry and Pharmaceutical Chemistry; and Deputy Director, Mass Spectrometry Facility, University of California, San Francisco, as well as Professor Emeritus, Department of Physiology and Biophysics, College of Medicine, University of California, Irvine, Irvine, CA. He is also Editor of the journal Molecular Cellular Proteomics Edward A. Dennis is Distinguished Professor and former Chair of the Department of Chemistry and Biochemistry and Professor in the Department of Pharmacology in the School of Medicine at the University of California, San Diego. He is also Editor-in-Chief of the Journal of Lipid Research.

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