Overview

Given the number of exciting developments across the whole spectrum of receptor research in recent years, the editors have not restricted themselves to one particular approach or class of receptors. Thus the studies within range from G protein-coupled surface receptors, to the delivery of antisense DNA inside living cell systems. A distinguished team of contributors cover these diverse areas, identifying any difficulties likely to be encountered and appropriate steps to overcome them.Wherever appropriate, the theoretical basis of each topic is explained first so that the results emerging from the practical procedures can be fully understood. Anyone with an interest in receptor structure and function will find this book an invaluable resource.

Full Product Details

Author:   Clare Stanford (Department of Pharmacology, University College London, UK) ,  Roger Horton (Department of Pharmacology, St.George's Hospital Medical School, London, UK)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Volume:   253
Dimensions:   Width: 19.00cm , Height: 1.90cm , Length: 24.60cm
Weight:   0.696kg
ISBN:  

9780199638826

ISBN 10:   0199638829
Pages:   312
Publication Date:   29 November 2001
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

1: Gerardo Turcatti: Probing G protein-coupled receptors by fluorescence spectroscopy 2: Hans-Peter Nothacker, Rainer K Reinscheid and Olivier Civelli: From receptor to endogenous ligand 3: Dianne M Perez, Michael J Zuscik, Sean A Ross and David J J Waugh: Point mutations and chimeric receptors in studies of ligand binding domains 4: F Anne Stephenson and Lynda M Hawkins: Determination of the subunit composition of native and cloned NMDA receptors 5: Dmitry M Gakamsky, Richard G Posner and Israel Pecht: Evaluating receptor stoichiometry by fluorescence resonance energy transfer (FRET) 6: Raymond Molloy, Antoine Robert, James R Howe and Thomas E Hughes: Monitoring intracellular trafficking of receptors 7: J Michael Edwardson: Monitoring the turnover kinetics of G protein-coupled receptors 8: Martyn Wood and Darren Smart: Real time receptor function in vitro: microphysiometry and fluorometric imaging plate reader (FLIPR) 9: Bernard J McDonald and Richard L Huganir: Regulation of receptors and receptor-coupled ion channels by protein phosphorylation 10: Ghassan Bkaily, Danielle Jacques, Pedro d'Orleans-Juste, Ghada Hassan and Sana Choufani: Using confocal imaging to measure changes in intracellular ions 11: B Scott Nunez and Wayne V Vedeckis: Monitoring nuclear receptor function 12: M Ian Phillips, Keping Qian and Dagmara Mohuczy: In vivo gene transfer of antisense to receptors

Reviews

[A] fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science [A] fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science [A] fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science [A] fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science [A] fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science A fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science

[A] fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science<br>

"""[A] fine book for those in search of new experimental approaches ... a well-marked trail ...""--Journal of Cell Science"

[A] fine book for those in search of new experimental approaches ... a well-marked trail ... --Journal of Cell Science

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