Overview

Receptor Purification is a unique practical two-volume guide to the purification of most receptor types including receptors for neurotransmitters polypeptide hormones steroid hormones and a variety of other ligands involved in many biological processes. Today's methods of receptor purification have evolved from years of research on the mechanisms of receptor actions where they were needed to discover receptor properties and ultimately for use in cloning. Receptor Purification provides a comprehensive source of techniques to enable the purification of cloned receptors as well as a handy reference on purification of receptors from cells and tissues in a physiological context. Designed to give investigators the best possible selection of approaches to a purification problem alternative methods are provided where applicable. In addition Receptor Purification features chapters on specific agents-such as covalent binding ligands-that will greatly simplify some purification processes. Many of the leading laboratories whose work has led to the purification of a wide variety of receptors are represented in the contributions to these two volumes. In some chapters information has been added on the applications of purified receptors while others focus on the cloning of the receptors. The purification of receptors is group-based on functional ligands. The first volume is devoted to the purification of receptors that bind neurotransmitters and a wide variety of polypeptide hormones. Volume 2 covers the steroid receptors and associated proteins such as vitamin D-3 and retinoic acid receptors. Other polypeptide receptors such as those involved in

Full Product Details

Author:   Gerald Litwack
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1991 ed.
Volume:   2
Dimensions:   Width: 17.80cm , Height: 2.30cm , Length: 25.40cm
Weight:   1.004kg
ISBN:  

9780896031838

ISBN 10:   0896031837
Pages:   417
Publication Date:   30 October 1990
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Dexamethasone 21-Mesylate: Applications for Purification and Examination of Glucocorticoid Receptors.- Dexamethasone-Biotin Affinity Probes: Partial Purification of the Human Spleen Tumor Glucocorticoid Receptor.- Purification of the Unactivated/Nontransformed Glucocorticoid Receptor Complex from Rat Tissues.- Purification of the Glucocorticoid Receptor and Its Ligand-Binding Domains.- Glucocorticoid Receptor Purification.- Glucocorticoid Receptor Purification and Characterization Using Tissue Culture Cells.- The Glucocorticoid Receptor:Purification and Characterization.- Purification of the Rat Kidney Mineralocorticoid Receptor.- Purification of the Androgen Receptor.- Purification of the Estrogen Receptor.- Estrogen Receptor Purification.- Progesterone Receptor Purification.- Purification of the Nontransformed Avian Progesterone Receptor.- Purification and Characterization of Chicken Progesterone Receptor.- 1,25-Dihydroxyvitamin D Receptor Purification and Structural Determination.- Retinoic Acid-Binding Protein.- Receptor Purification of the Thyroid Hormone Receptor.- The Vasopressin V1 Receptor: Purification, Characterization and Analysis of VI Receptor Interaction(s) with GuanineNucleotide-Binding Proteins.- Purification of an Angiotensin II Receptor.- Purification of Prostaglandin E1/Prostacyclin Receptors of Human Blood Platelets.- The Asialoglycoprotein Receptor.- Periplasmic and Membrane Receptors of Bacterial Chemotaxis.- Index 413.

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