Receptor and Ion-Channel Trafficking: Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels

Author:   Stephen J. Moss (, MRC-LMCB & Department of Pharmacology, University College London, UK) ,  Jeremy Henley (, MRC Centre for Synaptic Plasticity, School of Medical Sciences, University of Bristol, UK)
Publisher:   Oxford University Press
ISBN:  

9780192632241


Pages:   236
Publication Date:   22 August 2002
Format:   Hardback
Availability:   Out of stock   Availability explained
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Receptor and Ion-Channel Trafficking: Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels


Overview

A volume in the Molecular and Cellular Neurobiology series. This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states. The first section of the book contains three chapters dealing with cation channels and provides an accessible, succinct and comprehensive account of what is known about the structures and the assembly and targeting of these multimeric proteins. The focus of the book then moves on to cover ligand-gated ion channels with two chapters on acetylcholine receptors. The final section of the book contains four chapters covering the excitatory and inhibitory amino acid receptors. Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.

Full Product Details

Author:   Stephen J. Moss (, MRC-LMCB & Department of Pharmacology, University College London, UK) ,  Jeremy Henley (, MRC Centre for Synaptic Plasticity, School of Medical Sciences, University of Bristol, UK)
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Dimensions:   Width: 17.40cm , Height: 1.80cm , Length: 24.80cm
Weight:   0.646kg
ISBN:  

9780192632241


ISBN 10:   0192632248
Pages:   236
Publication Date:   22 August 2002
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Ion Channels 1: Malik-Hall, Wood & Okuse: Voltage-gated sodium channels 2: Tinker: The assembly and targeting of potassium channels 3: Dolphin: Assembly and targeting of voltage-dependent calcium channels Acetylcholine Receptors 4: Swope: Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve-muscle synapse 5: Millar: Assembly and targeting of neuronal nicotinic acetylcholine receptors Amino Acid Receptors 6: Stricker & Huganir: AMPA/kainate receptors 7: Hering & Sheng: NMDA receptor targeting 8: Harvey, von der Nuell & Harvey: Structure, assembly and targeting of glycine receptors 9: Luscher: GABAA and GABAC receptors: regulation of assembly, localization, clustering and turnover

Reviews

The editors and authors have done an excellent job ... Moss and Henley make a valuable contribution by highlighting major advances in the membrane trafficking of specific neurotransmitter receptors and ion channels ... this book is a most interesting and thought-provoking read. Nature Cell Biology


"""The editors and authors have done an excellent job ... Moss and Henley make a valuable contribution by highlighting major advances in the membrane trafficking of specific neurotransmitter receptors and ion channels ... this book is a most interesting and thought-provoking read."" Nature Cell Biology"


""The editors and authors have done an excellent job ... Moss and Henley make a valuable contribution by highlighting major advances in the membrane trafficking of specific neurotransmitter receptors and ion channels ... this book is a most interesting and thought-provoking read."" Nature Cell Biology


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