Overview

Award winning basic scientists and clinical researchers summarize the wealth of new molecular knowledge that sees cancer as a disease process involving key regulatory pathways. Emphasizing prevention, early diagnosis, prognosis, and treatment, these authoritative experts from around the world illuminate the variety of molecular markers to be found, interpret what is known about diseased regulatory pathways, and examine those future research directions likely to realize the promise of molecular therapy. From their presentations, readers will gain an understanding of why current therapies fail, and of the new processes now available to identify specific molecular targets for optimal therapeutic efficacy. Comprehensive and path-breaking, Principles of Molecular Oncology offers both basic and clinical oncologists not only a bold synthesis of the rapid and complex advances in molecular biology that are transforming our knowledge of cancer, but also a highly practical guide to today's strategies for its diagnosis and treatment.

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9781603277853

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Reviews

All the aspects of this complex and rapidly moving field are covered in this excellent book. Clinical oncologists will find a series of balanced reviews of the current state-of-the-art of the diagnosis and treatment of cancer based on molecular technology, and since cancer touches almost every field of clinical practice, specialists in other disciplines will find a very lucid and readable account of what is happening in one of the genuine success stories of molecular medicine. <br> From the foreword by Sir David Weatherall, FRS, Institute of Molecular Medicine, Oxford University, UK <br> Principles of Molecular Oncology provides a bold new look at the evolution of our knowledge of cancer. Authors from many disciplines are bringing together the facets that provide a comprehensive view of the whole...The reader will enjoy the opportunity to pause and look at the whole field as it stands today. The book will be both informative and intellectually stimulating. <br> From the foreword by E. Donnall Thomas, MD, Fred Hutchinson Cancer Research Center and Nobel Laureate in Medicine/Physiology, 1990 <br> Practicing physicians and advanced medical students as well as biochemists, molecular biologiests, and geneticists involved in the identification of molecular markers, therapeutic targets, and the underlying basis of cancer will all benefit from the addition of Principles of molecular oncology to their bookshelves. --The Lancet <br> .,. an excellent book devoted to exponentially evolving molecular oncology. The book under review covers the most important recent developments in the field of molecular oncology of human tumors in the way that can be understandable not only to clinical oncologistsworking in the field, but also to researchers of other fields as well. -Neoplasma <br> 'Principles of Molecular Oncology' gives an up-to-date and comprehensive account of the revolution in molecular biology over the last few decades and its relevance to laboratory and clinical oncology....The book is clearly set out, with largely well conceived and descriptive illustrations....the scope and detail of scientific data provided means that even those well grounded in molecular biology will find much of novel value. ...The major strength of this book lies in the ultimate section on future therapies....In summary, this book is a detailed informative summary of current knowledge of molecular oncology, with relevance both to the general oncologist and those interested in basic molecular research. - Annals of Oncology <br> .,. is a useful text for both new and experienced investigators in cancer genetics. It provides a framework for learning how to evaluate the diagnostic, prognostic, and predictive value of the myriad new cancer-genetic alterations that will result from the HGP. -The American Society of Human Genetics <br> .,. presents a rather comprehensive 'state-of-the-art' of progress made during the past two decades in understanding the molecular bases of cancer. - Biochimie

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