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OverviewOligonucleotides diffuse poorly through biological barriers, including cell membranes. They are also rapidly degraded in vivo by nucleuses. Aiming to improve the administration of compounds, the book studies the development of nucleotide chemistry. Full Product DetailsAuthor: Patrick Couvreur , Claude MalvyPublisher: Taylor & Francis Ltd Imprint: Taylor & Francis Ltd Dimensions: Width: 17.40cm , Height: 2.50cm , Length: 24.60cm Weight: 0.882kg ISBN: 9780748408412ISBN 10: 074840841 Pages: 336 Publication Date: 16 December 1999 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Unknown Availability: Out of stock Table of Contents1. Mechanisms of Action of Antisense Oligonucleotides D.M. Tidd and R.V. Giles 2. Chemistry of Oligonucleotides J.W. Engels and E. Uhlmann 3. The Oligonucleotide Prodrug Approach: The Pro-oligonucleotides F. Morvan, J.-J. Vasseur, E. Vives, B. Rayner and J.-L. Imbach 4. Peptide Nucleic Acids P.E. Nielsen 5. Peptide-mediated Delivery of Oligonucleotides E. Vives and B. Lebleu 6. Polymeric Nanoparticles and Microparticles as Carriers for Antisense Oligonucleotides E. Fattal and P.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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