Overview

An overview of the current understanding of how phagocytes recognize and respond to potentially pathogenic microbes. Provides a current understanding of the role of the phagocyte in host defense. Details the range of professional phagocyte cell lineages, including macrophages, PMNs, and dendritic cells. Outlines the functions of and challenges to the professional phagocyte. Improves our understanding of the cellular basis of antimicrobial responses. Integrates cell and molecular biology with immunological perspectives. This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

Full Product Details

Author:   David G Russell ,  Siamon Gordon
Publisher:   American Society for Microbiology
Imprint:   American Society for Microbiology
Dimensions:   Width: 22.10cm , Height: 3.20cm , Length: 28.40cm
Weight:   1.718kg
ISBN:  

9781555814014

ISBN 10:   1555814018
Pages:   584
Publication Date:   27 July 2009
Audience:   College/higher education ,  General/trade ,  Tertiary & Higher Education ,  General
Format:   Hardback
Publisher's Status:   Unknown
Availability:   In Print  
Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock.

Table of Contents

Table of Contents Foreword: What Would Darwin Have Said? Samuel C. Silverstein Part 1: Biology of the Professional Phagocyte 1. Neutrophils Forever Taco W. Kuijpers, Timo K. van den Berg, and Dirk Roos 2. Macrophages: Microbial Recognition and Response Annette Pluddemann and Siamon Gordon 3. Dendritic Cells and Their Tissue Microenvironment during Exposure to Pathogens A. Mortellaro, F. Granucci, M. Foti, and P. Ricciardi-Castagnoli Part 2: Membrane Receptors: Recognition, Adhesion, Phagocytosis, Chemotaxis, and Migration 4. Fc Receptors and Phagocytosis Steven Greenberg and Benjamin M. Dale 5. Chemokines and Phagocyte Trafficking Timothy J. Williams and Sara M. Rankin 6. Toll-Like Receptors Ricardo T. Gazzinelli, Kate Fitzgerald, and Douglas T. Golenbock 7. C-Type Lectins: Multifaceted Receptors in Phagocyte Biology Alessandra Cambi and Carl G. Figdor 8. Integrins on Phagocytes Wouter L. W. Hazenbos and Eric J. Brown 9. Intracytosolic Sensing of Pathogens: Nucleic Acid Receptors, NLRs, and the Associated Responses during Infections and Autoinflammatory Diseases Thomas Henry and Denise M. Monack 10. Phagocytes as a Source of the Fluid-Phase Pattern Recognition Receptor PTX3: Interplay between Cellular and Humoral Innate Immunity Alberto Mantovani, Barbara Bottazzi, Andrea Doni, and Giovanni Salvatori 11. Leukocyte Chemotaxis Ann Wheeler and Anne J. Ridley Part 3: Phagocytosis: Signaling, Cytoskeleton, and the Phagosome 12. Signaling for Phagocytosis Joel A. Swanson 13. Membrane Trafficking during Phagosome Formation and Maturation Gregory D. Fairn, Elena Gershenzon, and Sergio Grinstein 14. Acidification of Endosomes and Phagosomes Sushmita Mukherjee and Frederick R. Maxfield 15. Actin-Based Motility in Professional Phagocytes Frederick S. Southwick 16. Functional Analysis of the Intraphagosomal Environment of the Macrophage: Fluorogenic Reporters and the Transcriptional Responses of Salmonella and Mycobacterium Robin M. Yates, Kyle H. Rohde, Robert B. Abramovitch, and David G. Russell Part 4: Bridging the Gap between the Innate and Acquired Immune Response 17. Novel Anti-Inflammatory and Pro-Resolution Lipid Mediators in Induction and Modulation of Phagocyte Function Charles N. Serhan and Julio Aliberti 18. Cytokines and Macrophages and Dendritic Cells: Key Modulators of Immune Responses Frank Kaiser and Anne O'Garra 19. Macrophage Classical Activation Donald C. Vinh and Steven M. Holland 20. The Functional Heterogeneity of Activated Macrophages Xia Zhang and David M. Mosser 21. Recognition and Removal of Apoptotic Cells Peter M. Henson and Donna L. Bratton 22. Regulation and Antimicrobial Function of Inducible Nitric Oxide Synthase in Phagocytes Christian Bogdan Part 5: Pathogens of the Professional Phagocyte 23. The Multiple Interactions between Salmonella and Phagocytes Jessica A. Thompson and David W. Holden 24. Legionella, a Pathogen of Amoebae and Macrophages Michele S. Swanson and Andrew Bryan 25. The Role of Phagocytic Cells during Shigella Invasion of the Colonic Mucosa Guy Tran Van Nhieu and Philippe Sansonetti 26. Autophagy: a Fundamental Cytoplasmic Sanitation Process Operational in All Cell Types Including Macrophages Vojo Deretic 27. Brucella, a Perfect Trojan Horse in Phagocytes Suzana P. Salcedo and Jean-Pierre Gorvel 28. Interaction of Candida albicans with Phagocytes Ines Faro-Trindade and Gordon D. Brown 29. The Parasite Point of View: Insights and Questions on the Cell Biology of Trypanosoma and Leishmania Parasite-Phagocyte Interactions Keith Gull 30. Phagocyte Interactions with the Intracellular Protozoan Toxoplasma gondii Eric Y. Denkers 31. Macrophages in Helminth Infection: Effectors, Regulators, and Wound Healers Judith E. Allen and Thomas A. Wynn Part 6: Models of Host-Pathogen Interactions 32. Dictyostelium discoideum: a Model Phagocyte and a Model for Host-Pathogen Interactions Zhiru Li and Ralph R. Isberg 33. Phagocytosis in Drosophila melanogaster Immune Response Vincent Leclerc, Jean-Marc Reichhart, Isabelle Caldelari, and Natalia Veresceaghina 34. The Zebrafish as a Model of Host-Pathogen Interactions J. Muse Davis and Lalita Ramakrishnan 35. Whole Genome Screens in Macrophages Babak Javid and Eric J. Rubin

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