Overview

Molecular biology is one of the most rapidly growing develo- ping and at thesame time most exciting disciplines. The key to molecular biology lies in the understanding of nucleic a- cids - their structure, function, and interaction with pro- teins. Nucleic Acids and Molecular Biology keeps scientists informed of the explosively growing information and complies with with the great interest in this field by offering a continued high standard of review. A substantial part of this volume has been devoted to the analysis of different aspects of nucleic acid-protein-interactions including RNA- protein-interaction.

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Author:   Fritz Eckstein ,  David M. J. Lilley
Publisher:   Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Imprint:   Springer-Verlag Berlin and Heidelberg GmbH & Co. K
Edition:   Softcover reprint of the original 1st ed. 1993
Volume:   7
Dimensions:   Width: 15.50cm , Height: 1.90cm , Length: 23.50cm
Weight:   0.540kg
ISBN:  

9783642779527

ISBN 10:   3642779522
Pages:   341
Publication Date:   08 December 2011
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

DNA, cis-Platinum and Intercalators: Catalytic Activity of the DNA Double Helix.- Indirect Effects of DNA Sequence on 434 Repressor-DNA Interactions.- E. coli Met Repressor: DNA Recognition by ?-Strands.- Mechanism of Action of Restriction Endonuclease EcoRV.- DNA Bending by Fos and Jun: Structural and Functional Implications.- Structure of the TFIIIA-DNA Complex.- Structure and Function of the Glucocorticoid Receptor DNA-Binding Domain.- Retinoid Receptors and Their Role in Cellular Proliferation and Differentiation.- Structural and Functional Aspects of the DNA Binding Protein FIS.- LexA, the Self-Cleaving Transcriptional Repressor of the SOS System.- Resolution of Holliday Junctions by the E. coli RuvC Protein.- Site-Specific Recombination and the Segregation of Circular Chromosomes.- Nucleosome Positioning.- The Role of the Nucleoskeleton in RNA Metabolism.- The Mechanism of Action of the Retinoblastoma Gene Product.- RNA Pseudoknots.- Selection of Functional RNA and DNA Molecules from Randomized Sequences.- Structure and Function of Ribonuclease HI from Escherichia coli.- RNA-Protein Interactions in Ribonucleoprotein Particles.- Hybrid States of tRNA During Translation.

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