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Author:   Tony Yaksh ,  Salim Hayek
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2023
Weight:   2.715kg
ISBN:  

9783031395574

ISBN 10:   3031395573
Pages:   830
Publication Date:   03 January 2024
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

History and Evolution of Intrathecal Drug Delivery.- Intraspinal Anatomy: Considerations in Intrathecal Drug Delivery.- Spinal Target Receptors in Intrathecal Drug Delivery.- Mechanisms of Action of Intrathecally Administered Agents.- Physicochemical Properties and Compounding of Intrathecally Administered Agents.- Cerebrospinal Fluid Flow Dynamics.- Uptake and Distribution of Intrathecally Administered Agents.- Animal Models of Intrathecal Drug Delivery: Clinical Correlates.- Intrathecal Drug Delivery for Pain: Medical Considerations.- Intrathecal Drug Delivery for Pain: Psychological Considerations.- Intrathecal trialing Techniques for Pain Indications.- Catheter Localization and Programming Parameters for Pain.- Maintenance and Troubleshooting of Intrathecal Therapy for Pain.- Intrathecal Agents: Choices for Pain.- Intrathecal Therapy for Cancer Pain: Best Practices.- Intrathecal Therapy for Non-Cancer Pain: Best Practices.- Managing Complications of Intrathecal Therapy for Pain.- Assessing Patients with Movement Disorders for Intrathecal Therapy.- Trialing Techniques for Spasticity.- Catheter Localization and Programming Parameters for Spasticity.- Intrathecal Agents Use for Spasticity.- Maintenance and Troubleshooting of Intrathecal Therapy for Spasticity.- Managing Complications of Intrathecal Therapy for Spasticity.- System Choices.- Implantation Techniques.- Preoperative Considerations.-   Managing Surgical Complications.- ;Special Patient Populations (Children, Anticoagulation, Other implanted devices) .- Cost Effectiveness of Intrathecal Drug Delivery.- Keys to Managing a Successful Targeted Drug Delivery Practice.- Targeted Drug Delivery: Beyond the Spinal Canal.

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Author Information

Salim M. Hayek, MD, PhD University Hospitals of Cleveland Division of Pain Medicine Department of Anesthesiology Cleveland, OH USA   Tony L. Yaksh, PhD University of California, San Diego Department of Anesthesiology and Pharmacology La Jolla, CA USA

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