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OverviewIn this book the targets of drug action are the central focus - whether they be enzymes in a pathway or membrane-bound receptors and ion channels. This approach distinguishes the book from others in the f ield which consider the subject mainly in terms of disease.; The introductory chapter is concerned with the basic principles that cover enzyme inhibition and receptor binding by drugs. The next seven chapters deal with drugs that modulate biochemical pathways, both of synthesis and breakdown, while the last four chapters are concerned with organizational structures of the cell.; The book brings together the state of knowledge with respect to drug action and emphasizes mechanistic aspects of drug action. It encompasses the modes of action of drugs for infectious disease and those for endogenous conditions. There is a listing of reviews and essay questions are provided for each chapter. Full Product DetailsAuthor: Christopher J. Coulson (Glaxo, New Barnet, UK)Publisher: Taylor & Francis Ltd Imprint: Taylor & Francis Ltd Edition: 2nd New edition Dimensions: Width: 15.60cm , Height: 2.00cm , Length: 23.50cm Weight: 0.653kg ISBN: 9780748400683ISBN 10: 0748400680 Pages: 300 Publication Date: 03 February 1994 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Out of Print Availability: In Print Limited stock is available. It will be ordered for you and shipped pending supplier's limited stock. Table of ContentsGeneral principles; nucleic acid biosynthesis and catabolism; protein biosynthesis; carbohydrate metabolism; cell wall biosynthesis; steroid biosynthesis and action; prostaglandin and leukotriene biosynthesis and action; zinc metalloenzymes; neurotransmitter action and metabolism; membrane active agents; microtubule assembly; hormonal modulators. Appendix: quantification of ligand/macromolecule binding.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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