Molecular Biology of Circadian Rhythms

Author:   Amita Sehgal
Publisher:   John Wiley and Sons Ltd
ISBN:  

9780471418245


Pages:   284
Publication Date:   01 April 2004
Format:   Hardback
Availability:   Out of stock   Availability explained


Our Price $369.47 Quantity:  
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Molecular Biology of Circadian Rhythms


Overview

Biological, or circadian, clocks govern such functions as sleeping and waking, rest and activity, body temperature, and oxygen consumption. Chronobiology strives to understand how cells generate circadian rhythms through molecular processes of transcription and translation. Drawing on the recent revolutionary advances in biology and genetics, Molecular Biology of Circadian Rhythms presents a comprehensive account of the current state of chronobiology, delivering a ready resource for students and practitioners. Editor Amita Sehgal assembles chapters contributed by leading experts in the molecular analysis of circadian rhythms, representing the state of the art in this emerging discipline. The text begins with a general introduction to biochemical and biophysical aspects of circadian timing, then proceeds to its essential focus on collating the newest information on molecular mechanisms of circadian rhythms. It includes a chapter on the implications for clinical research on affective disorders, sleep disorders, and the relevance for therapeutic treatment, as well as coverage of multiple oscillators and hormonal rhythms. Sections include: Molecular Control of Circadian Rhythms: Animal

Full Product Details

Author:   Amita Sehgal
Publisher:   John Wiley and Sons Ltd
Imprint:   John Wiley & Sons Inc
Dimensions:   Width: 18.10cm , Height: 2.10cm , Length: 25.70cm
Weight:   0.738kg
ISBN:  

9780471418245


ISBN 10:   0471418242
Pages:   284
Publication Date:   01 April 2004
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Out of Stock Indefinitely
Availability:   Out of stock   Availability explained

Table of Contents

Preface. Acronyms. PART I: INTRODUCTION TO CIRCADIAN RHYTHMS. 1. General Concepts (Amita Sehgal). 2. Genetic and Molecular Approaches Used to Analyze Rhythms (Amita Sehgal and Jeffrey L. Price). PART II: MOLECULAR CONTROL OF CIRCADIAN RHYTHMS: ANIMAL MODELS. 3. Drosophila melanogaster: A Model System for Molecular Chronobiology (Jeffrey L. Price). 4. Molecular Analysis of Circadian Rhythms: Nonmammalian Vertebrates (Julie A. Williams). 5. Genetic Basis for Circadian Rhythms in Mammals (John D. Alvarez). PART III: MOLECULAR CONTROL OF CIRCADIAN RHYTHMS: FROM CYANOBACTERIA TO PLANTS. 6. Circadian Rhythms in Cyanobacteria (Nirnjini Naidoo). 7. Molecular Analysis of Circadian Rhythms in Neurospora (Amita Sehgal). 8. Physiological and Molecular Characteristics of Plant Circadian Clocks (Jose A. Jarillo, Juan Capel, and Anthony R. Cashmore). PART IV: CIRCADIAN ORGANIZATION IN COMPLEX ORGANISMS. 9. Multiple Oscillators (Jadwiga M. Giebultowicz). 10. Hormonal Rhythms (Peter McNamara). 11. Human Circadian Rhythms (Hans P. A. Van Dongen, Gerard A. Kerkhof, and David F. Dinges). Index.

Reviews

""...a good introduction to anyone who is interested in learning about the molecular mechanisms behind circadian rhythms..."" (Cell Biochemistry and Function, Vol. 23 (4) July 2005) ""...valuable reading for biological or medical scientists and many practitioners. As a first in its field, the volume is sure to become a classic."" (Quarterly Review of Biology, March-May 2005) ""...a timely snapshot of the molecular mechanisms of biological timekeeping as we understand it today."" (Genes, Brain and Behavior, March 2005) ""...better than a good book...The Alvarez chapter alone justifies its purchase, and several other excellent chapters are also quite useful."" (Clinical Chemistry, January 2005) ""...presents a comprehensive account of the current state of chronobiology, delivering a ready resource for students and practitioners."" (Bio World (Germany), Vol.9, No.5 2004) ""...few other books on this subject are available. The material is on interest event to those not in the area."" (Doody's Health Services)


...a good introduction to anyone who is interested in learning about the molecular mechanisms behind circadian rhythms... (Cell Biochemistry and Function, Vol. 23 (4) July 2005) ...valuable reading for biological or medical scientists and many practitioners. As a first in its field, the volume is sure to become a classic. (Quarterly Review of Biology, March-May 2005) ...a timely snapshot of the molecular mechanisms of biological timekeeping as we understand it today. (Genes, Brain and Behavior, March 2005) ...better than a good book...The Alvarez chapter alone justifies its purchase, and several other excellent chapters are also quite useful. (Clinical Chemistry, January 2005) ...presents a comprehensive account of the current state of chronobiology, delivering a ready resource for students and practitioners. (Bio World (Germany), Vol.9, No.5 2004) ...few other books on this subject are available. The material is on interest event to those not in the area. (Doody's Health Services)


Author Information

Amita Sehgal received her Ph.D. in Cell and Molecular Biology from Cornell University Medical College. Her postdoctoral training was conducted at Rockefeller University, working on the genetic and molecular basis of circadian rhythms in the fruit fly. She has continued this line of work as an independent investigator at the University of Pennsylvania. She is currently an Associate Professor of Neuroscience and an Associate Investigator of the Howard Hughes Medical Institute.

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