Overview

Numerous studies have proven the biological basis of memory formation and have begun to identify the biochemical traces and cellular circuits that are formed by experience, and which participate in the storage of information in the brain, its retention for long durations, and its retrieval upon demand. Cells in the nervous system have the capability of undergoing extremely long-lasting alterations in response to hormonal, pharmacological, and environmental stimulations. The mechanisms underlying this neuronal plasticity are activated by experiential inputs and operate in the process of learning and the formation of memories in the brain. This volume presents research areas which have not been highlighted in the past. In addition to studies on the involvement of functional proteins in neuronal adaptation, this volume presents developments on the critical roles of bioactive lipids and nucleotides in these processes.

Full Product Details

Author:   Yigal H. Ehrlich
Publisher:   Springer Science+Business Media
Imprint:   Kluwer Academic/Plenum Publishers
Edition:   1998 ed.
Volume:   446
Dimensions:   Width: 15.50cm , Height: 1.60cm , Length: 23.50cm
Weight:   1.150kg
ISBN:  

9780306460401

ISBN 10:   0306460408
Pages:   229
Publication Date:   31 March 1999
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

1. Molecular Specificity of Synaptic Changes Responsible for Associative Memory.- 2. Behavioral and Mechanistic Bases of Long-Term Habituation in the Crab Chasmagnathus.- 3. Bioactive Lipids and Gene Expression in Neuronal Plasticity.- 4. Surface Protein Phosphorylation by Ecto-Protein Kinases: Role in Neuronal Development and Synaptic Plasticity.- 5. Extracellular ATP-Induced Apoptosis in PC 12 Cells.- 6. The Role of the Neural Growth Associated Protein B-50/Gap-43 in Morphogenesis.- 7. Avian Hippocampus as a Model to Study Spatial Orientation-Related Synaptic Plasticity.- 8. Metabotropic Glutamate Receptors in the Plasticity of Excitatory Responses in the Hippocampus: Clinical Impact.- 9. Familial Amyotrophic Lateral Sclerosis and Alzheimers Disease: Transgenic Models.- 10. Proteins Implicated in Alzheimer Disease: The Role of FE65, a New Adapter which Binds to ß-Amyloid Precursor Protein.- 11. Influence of Phospholipids and Sequential Kinase Activities on Tau in Vitro.- 12. Cell Culture Models of Neuronal Degeneration and Neuroprotection: Implications for Parkinson’s Disease.- 13. Aging and Dementia of the Alzheimer Type: In Persons with Mental Retardation.

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