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Author:   T. M. Schuster ,  T. M. Laue
Publisher:   Birkhauser Boston Inc
Imprint:   Birkhauser Boston Inc
Volume:   Vol 1
Dimensions:   Width: 16.30cm , Height: 2.20cm , Length: 24.20cm
Weight:   0.700kg
ISBN:  

9780817636746

ISBN 10:   0817636749
Pages:   354
Publication Date:   01 August 1994
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

I: Sedimentation Equilibrium.- Notes on the Derivation of Sedimentation Equilibrium Equations.- Association of REI Immunoglobulin Light Chain VL Domains: The Functional Linearity of Parameters in Equilibrium Analytical Ultracentrifuge Models for Self-Associating Systems.- Comments on the Analysis of Sedimentation Equilibrium Experiments.- The Omega Analysis and the Characterization of Solute Self- Association by Sedimentation Equilibrium.- Conservation of Signal: A New Algorithm for the Elimination of the Reference Concentration as an Independently Variable Parameter in the Analysis of Sedimentation Equilibrium.- Analysis of Protein-Nucleic Acid and Protein-Protein Interactions Using Multi-Wavelength Scans from the XL-A Analytical Ultracentrifuge.- II: Sedimentation Velocity.- Sedimentation Boundary Analysis of Interacting Systems: Use of the Apparent Sedimentation Coefficient Distribution Function.- Studies of Macromolecular Interaction by Sedimentation Velocity.- Measuring Sedimentation, Diffusion, and Molecular Weights of Small Molecules by Direct Fitting of Sedimentation Velocity Concentration Profiles.- Computer Simulation of the Sedimentation of Ligand-Mediated and Kinetically Controlled Macromolecular Interactions.- Refining Hydrodynamic Shapes of Proteins: The Combination of Data from Analytical Ultracentrifugation and Time-Resolved Fluorescence Anisotropy Decay.- III: Acquisition and Data Reduction.- On Line Data Acquisition for the Rayleigh Interference Optical System of the Analytical Ultracentrifuge.- Extensions to Commercial Graphics Packages for Customization of Analysis of Analytical Ultracentrifuge Data.- A Graphical Method for Determining the Ideality of a Sedimenting Boundary.- IV: Some Specific Examples.- Analytical Ultracentrifugation and Its Use in Biotechnology.- Applications of Analytical Ultracentrifugation in Structure-Based Drug Design.- The Sedimentation Equilibrium Analysis of Polysaccharides and Mucins: A Guided Tour of Problem Solving for Difficult Heterogeneous Systems.

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