Overview

Microbial biofilms are serious problem in medical settings as they are associated with significant mortality and morbidity. Infection related to biofilms not only increases recovery time, but also escalates the cost of disease management. Biofilms are intrinsically resistant to antibiotics and evade human defense mechanisms. In addition, the close proximity of microbes within biofilms promotes genetic transformation, facilitating the acquisition of antibiotic-resistant genes and leading to an increased prevalence of diseases associated with resistance. Fortunately, with advances in science and technology, novel strategies are being utilized to mitigate the impact of biofilms on human health. Microbial Biofilms: Role in Human Infectious Diseases focuses on new and emerging concepts in microbial biofilm research. It explores topics such as the mechanisms of biofilm formation, biofilm-induced pathogenesis, biofilm detection and diagnosis, gene exchange within biofilms, strategies to control microbial biofilms, and the burden of biofilm-associated infections. Additionally, the book highlights the various antibiofilm strategies, such as surface coating, signal quenching, novel compounds that can be translated to curb biofilm-associated infections, and the escalation of antimicrobial resistance determinants.

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9780443192524

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Dr. Mukesh Kumar Yadav, is working as an Associate Professor at the Department of Microbiology, Central University of Punjab, Bathinda, Punjab, India. He has more than 15 years of research experience in the field of microbiology in general and microbial biofilms, host-pathogen interaction and endophytes in particular. In his laboratory, Dr. Yadav’s is working on microbial biofilms, antimicrobial resistance, pathogenesis and identification of novel pathways for the development of new antimicrobial/antibiofilm compounds. Dr. Yadav has published more than 74 research articles and received research grants from various funding agencies like, NRF Korea, Indian Council of Medical Research (ICMR), Department of Science and Technology (DST), Department of Biotechnology (DBT) and University Grant Commission (UGC). Prof. Jae Jun Song is a Professor at Korea University College of medicine Seoul, South Korea. Prof. Song is clinical professional and has more than 15 years of research experience. He has published more than 80 research papers in peer-reviewed journals and has completed many research grants related to microbial biofilms Dr. Jorge E. Vidal is an Associate Professor in the Department of Cell and Molecular Biology and a member of the Center for Immunology and Microbial Research at the University of Mississippi Medical Center. In his research laboratory, Dr. Vidal studies the molecular mechanisms of bacterial pathogenesis, biofilm formation, and the mechanisms leading to the acquisition of antibiotic resistance. Dr. Vidal has published more than 100 research papers and has received several research grants from the NIH, BMGF, Pfizer, and other agencies.

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