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OverviewIn 1976 I wrote a monograph on lysosomes (Lysosomes: A Survey, Springer Verlag, Vienna) that was intended as an up-to-date, comprehensive survey. Whatever success I may have achieved then in fulfilling that intention, even the effort now would be foolhardy. The literature has grown so rapidly in the past decade that I certainly could not even read all of the essential papers, let alone understand and analyze them. My goal here, therefore, is simply to introduce the major features of lysosomes at a level I hope will be useful both to I;ldvanced students and to researchers interested in obtaining a broad background. This is in keeping with the design of the Cellular Organelles series: the series is more a set of advanced texts than of review monographs. This design carries with it the decision not to support each point by refer ences to the original literature. I apologize for the injustice involved in such a decision but feel that in any event it would be impossibly unwieldy to cite, adequately and in a balanced manner, the contributions of the vast network of researchers responsible for the information upon which I draw. Full Product DetailsAuthor: Eric HoltzmanPublisher: Springer Science+Business Media Imprint: Kluwer Academic/Plenum Publishers Edition: 1989 ed. Dimensions: Width: 17.80cm , Height: 2.50cm , Length: 25.40cm Weight: 2.400kg ISBN: 9780306429668ISBN 10: 0306429667 Pages: 440 Publication Date: 31 January 1989 Audience: College/higher education , Professional and scholarly , Undergraduate , Postgraduate, Research & Scholarly Format: Hardback Publisher's Status: Active Availability: In Print This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of Contents1 Historical Fragments; Methods; Some Terminology.- 2 Endocytosis and Heterophagy.- 3 Acidification; Membrane Properties; Permeability and Transport.- 4 Uses and Abuses of Endocytotic and Heterophagic Pathways.- 5 Autophagy and Related Phenomena.- 6 Extensive Release. Excessive Storage.- 7 Genesis.ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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