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OverviewLandmark Experiments in Molecular Biology Full Product DetailsAuthor: Michael Fry (Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Haifa, Israel)Publisher: Elsevier Science Publishing Co Inc Imprint: Academic Press Inc Dimensions: Width: 15.20cm , Height: 3.00cm , Length: 22.90cm Weight: 0.860kg ISBN: 9780128020746ISBN 10: 0128020741 Pages: 570 Publication Date: 08 July 2016 Audience: Professional and scholarly , Professional & Vocational Format: Paperback Publisher's Status: Active Availability: Manufactured on demand We will order this item for you from a manufactured on demand supplier. Table of ContentsCHAPTER 1: Introduction CHAPTER 2: Prehistory of Molecular Biology: 1847-1944 CHAPTER 3: Avery Identifies DNA as the Genetic Material CHAPTER 4: Hershey and Chase Clinch the Role of DNA as the Genetic Material CHAPTER 5: Watson and Crick Solve the Structure of DNA CHAPTER 6: Meselson and Stahl Demonstrate that DNA is Replicated Semiconservatively CHAPTER 7: Defining the Genetic Code CHAPTER 8: The Adaptor Hypothesis and the Isolation of transfer RNA CHAPTER 9: The Discovery and Rediscovery of messenger RNA CHAPTER 10: Deciphering the Genetic Code CHAPTER 11: The Surprising Discovery of Split Genes and RNA Splicing Chapter 12: Epilogue, Theory-driven versus experiment-directed discoveries in molecular biologyReviewsThe title of the book perfectly summarizes Michael Fry's aim: to present in a simple educational way the most beautiful and significant experiments in the history of molecular biology. The most significant contribution of this publication is probably the beautiful and precise experimental illustrations that have been specially drawn to accompany an equally precise and complete description of the experiments described in the book. Michael Fry has also added a long list of references, to the original articles, to the comments made by the scientists involved, and to the work of historians. This book will be useful, but the historian will not be wholly happy with it. What is missing.... in the book in general, is a meta-level of interpretation not limited to that of the participants, a meta-level mixing analysis of the context, philosophical issues not limited to the too general debate on the opposition between theory and experiment, and a precise study of the dynamics of the events that led to the discovery. Maybe Michael Fry was too modest and too admiring of the work that was accomplished to do what a historian would expect: resurrect the context that even the participants have often forgotten and sometimes never clearly distinguished, to show how tortuous the pathway of discovery was, how the ideas that led to the truth were often wrong. This 'unvarnished' history, leaving as much space to mistakes as to successes, is the only one that can be truly useful to future scientists. -- Professor Michel Morange, History and Philosophy of the Life Sciences """The title of the book perfectly summarizes Michael Fry’s aim: to present in a simple educational way the most beautiful and significant experiments in the history of molecular biology. The most significant contribution of this publication is probably the beautiful and precise experimental illustrations that have been specially drawn to accompany an equally precise and complete description of the experiments described in the book. Michael Fry has also added a long list of references, to the original articles, to the comments made by the scientists involved, and to the work of historians. This book will be useful, but the historian will not be wholly happy with it. What is missing.... in the book in general, is a meta-level of interpretation not limited to that of the participants, a meta-level mixing analysis of the context, philosophical issues not limited to the too general debate on the opposition between theory and experiment, and a precise study of the dynamics of the events that led to the discovery. Maybe Michael Fry was too modest and too admiring of the work that was accomplished to do what a historian would expect: resurrect the context that even the participants have often forgotten and sometimes never clearly distinguished, to show how tortuous the pathway of discovery was, how the ideas that led to the truth were often wrong. This ‘unvarnished’ history, leaving as much space to mistakes as to successes, is the only one that can be truly useful to future scientists."" -- Professor Michel Morange, History and Philosophy of the Life Sciences" The title of the book perfectly summarizes Michael Fry's aim: to present in a simple educational way the most beautiful and significant experiments in the history of molecular biology. The most significant contribution of this publication is probably the beautiful and precise experimental illustrations that have been specially drawn to accompany an equally precise and complete description of the experiments described in the book. Michael Fry has also added a long list of references, to the original articles, to the comments made by the scientists involved, and to the work of historians. This book will be useful, but the historian will not be wholly happy with it. What is missing.... in the book in general, is a meta-level of interpretation not limited to that of the participants, a meta-level mixing analysis of the context, philosophical issues not limited to the too general debate on the opposition between theory and experiment, and a precise study of the dynamics of the events that led to the discovery. Maybe Michael Fry was too modest and too admiring of the work that was accomplished to do what a historian would expect: resurrect the context that even the participants have often forgotten and sometimes never clearly distinguished, to show how tortuous the pathway of discovery was, how the ideas that led to the truth were often wrong. This `unvarnished' history, leaving as much space to mistakes as to successes, is the only one that can be truly useful to future scientists. -- Professor Michel Morange, History and Philosophy of the Life Sciences Author InformationDepartment of Biochemistry, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, POB 9649, Bat Galim, Haifa, 31096, Israel Tab Content 6Author Website:Countries AvailableAll regions |
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