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OverviewA key question regarding the action of IL-5 in responsive cells has been the molecular mechanism of signal transduction cascade after IL-5 binding to the functional IL-5 receptor (IL-5R). In this volume the history of the initial discovery of the IL-5 activity that appeared to be involved in growth and differentiation of B cells and eosinophils is first briefly summarized, and the developments that lead to the molecular characterization of IL-5 are outlined. The author also describes recent advances of IL-5 and IL-5R research in the study of structure, physiologic functions and unique modes of receptor-mediated signalling. Finally, the roles of IL-5 in the pathophysiology of allergic diseases and immunodeficiency are described. Full Product DetailsAuthor: Kiyoshi TakatsuPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: illustrated edition Weight: 0.695kg ISBN: 9783540592129ISBN 10: 3540592121 Pages: 176 Publication Date: 22 June 1995 Audience: College/higher education , Professional and scholarly , Postgraduate, Research & Scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: Out of stock The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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