Overview

This handbook provides the first comprehensive overview of the emerging field of glycomics, defined as the study of all complex carbohydrates in an organism or cell ( the glycome ). Beginning with analytic approaches and bioinformatics, this work provides a detailed discussion of relevant databases, data integration, and analysis. It then moves on to a discussion of specific model organism and pathogen glycomes followed by therapeutic approaches to human disorders of glycosylization. Structure and function of glycomes are included along with state-of-the-art technologies and systems approaches to the analysis of glycans. * Synthesizes contributions from experts in biology, chemistry, bioinformatics, biotechnology, and medicine * Highlights chapters devoted to chemical synthesis, cancer glycomics and immune cell glycomics * Includes discussions of proteomics, mass spectrometry, NMR, array technology, and transcriptomics analytic approaches

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9781282737310

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