Genomic Imprinting
Author:   Wolf Reik ,  Azim Surani
Publisher:   Oxford University Press
Volume:   No.18
ISBN:  

9780199636266


Pages:   268
Publication Date:   01 November 1997
Format:   Hardback
Availability:   To order   Availability explained
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Genomic Imprinting


Overview

Genomic imprinting, the differential marking of genes inherited from paternal and maternal sources, has been recognized since the late 1970s and is known to be involved in several inherited diseases. However, it is only very recently that questions surrounding the mechanisms of genomic imprinting have begun to be answered. This volume reviews the latest exciting developments, with full citations of all of the key bibliography. It also discusses the major unanswered questions in this field and outlines directions for future research. This book is intended for post-graduate and post-doctoral researchers and academic staff.

Full Product Details

Author:   Wolf Reik ,  Azim Surani
Publisher:   Oxford University Press
Imprint:   Oxford University Press
Volume:   No.18
Dimensions:   Width: 18.00cm , Height: 2.00cm , Length: 24.00cm
Weight:   0.740kg
ISBN:  

9780199636266


ISBN 10:   0199636265
Pages:   268
Publication Date:   01 November 1997
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   To order   Availability explained
Stock availability from the supplier is unknown. We will order it for you and ship this item to you once it is received by us.

Table of Contents

Role of DNA methylation in mammalian development; developmental regulation of imprinting by DNA methylation; imprinting at the mouse and human IGF2R loci; function and epigenetic modification of the imprinted H19 gene; the imprinted insulin-like growth factor 2 gene; consequences of genomic imprinting for foetal development; genomic imprinting in the mouse - possible final analysis; systematic approaches for the identification of imprinted genes; genomic imprinting as a developmental process disturbed in cancer; imprinting in the Prader-Willi/Angelman syndrome region on human chromosome 15; convergent themes in X chromosome inactivation and autosomal imprinting; evolutionary theories of genomic imprinting.

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