DNA Methylation: Molecular Biology and Biological Significance

Author:   J. Jost ,  H. Saluz
Publisher:   Birkhauser Verlag AG
Edition:   1993 ed.
Volume:   64
ISBN:  

9783764327781


Pages:   572
Publication Date:   01 November 1992
Format:   Hardback
Availability:   Out of stock   Availability explained


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DNA Methylation: Molecular Biology and Biological Significance


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Author:   J. Jost ,  H. Saluz
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   1993 ed.
Volume:   64
Weight:   1.270kg
ISBN:  

9783764327781


ISBN 10:   3764327782
Pages:   572
Publication Date:   01 November 1992
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock   Availability explained

Table of Contents

A chronicle of DNA methylation (1948–1975).- Major techniques to study DNA methylation.- Methylation of cytosine influences the DNA structure.- Methylation of DNA in prokaryotes.- Structure, function and regulation of mammalian DNA methyltransferase.- Regulation of the de novo methylation.- Effect of DNA methylation on the binding of vertebrate and plant proteins to DNA.- CpG Islands.- DNA methyltransferases and DNA site-specific endonucleases encoded by chlorella viruses.- Control of DNA methylation in fungi.- The role of DNA methylation in the regulation of plant expression.- Pattern of de novo methylation and promoter inhibition: studies on the adenovirus and the human genome.- DNA methylation and retrovirus expression.- Effect of DNA methylation on dynamic properties of the helix and nuclear protein binding in the H-ras promoter.- DNA methylation and embryogenesis.- X chromosome inactivation and DNA methylation.- DNA methylation: Its possible functional role in developmental regulation of human globin gene families.- DNA methylation, chromatin structure and the regulation of gene expression.- Steroid hormone-dependent changes in DNA methylation and its significance for the activation or silencing of specific genes.- Epigenetic inheritance based on DNA methylation.- DNA methylation and genomic imprinting in mammals.- DNA methylation and cancer.- The repair of 5-methylcytosine deamination damage.- Gene methylation patterns and expression.

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