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Author:   Vladimir N Uversky (Department of Molecular Medicine and USF Health Byrd Alzheimer’s Research Institute, Morsani College of Medicine, University of South Florida, Tampa, FL, United States)
Publisher:   Elsevier Science & Technology
Imprint:   Academic Press Inc
Weight:   0.450kg
ISBN:  

9780323852999

ISBN 10:   0323852998
Pages:   434
Publication Date:   19 October 2021
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

1. Intrinsic disorder and phase transitions: Pieces in the puzzling role of the prion protein in health and disease Mariana J. do Amaral and Yraima Cordeiro 2. Functions of intrinsically disordered proteins through evolutionary lenses Mátyás Pajkos and Zsuzsanna Dosztányi 3. Non-specific porins of Gram-negative bacteria as proteins containing intrinsically disordered regions with amyloidogenic potential Olga D. Novikova, Vladimir N. Uversky and Elena A. Zelepuga 4. Intrinsic disorder in integral membrane proteins Brian J. Aneskievich, Rambon Shamilov and Olga Vinogradova 5. Molecular simulations of IDPs: From ensemble generation to IDP interactions leading to disorder-to-order transitions Hebah Fatafta, Suman Samantray, Abdallah Sayyed-Ahmad, Orkid Coskuner-Weber and Birgit Strodel 6. Target-binding behavior of IDPs via pre-structured motifs Do-Hyoung Kim and Kyou-Hoon Han 7. The role of dancing duplexes in biology and disease Heather M. Forsythe and Elisar Barbar 8. Intrinsic disorder in protein kinase A anchoring proteins signaling complexes Mateusz Dyla and Magnus Kjaergaard 9. Protein intrinsic disorder on a dynamic nucleosomal landscape Sveinn Bjarnason, Sarah F. Ruidiaz, Jordan McIvor, Davide Mercadante and Pétur O. Heidarsson 10. Flexible spandrels of the global plant virome: Proteomic-wide evolutionary patterns of structural intrinsic protein disorder elucidate modulation at the functional virus–host interplay Rachid Tahzima, Annelies Haegeman, Sébastien Massart and Eugénie Hébrard

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Prof. Vladimir N. Uversky, PhD, DSc, FRSB, FRSC, F.A.I.M.B.E., Professor at the Department of Molecular Medicine, Morsani College of Medicine, University of South Florida (USF), is a pioneer in the field of protein intrinsic disorder. He has made a number of groundbreaking contributions in the field of protein folding, misfolding, and intrinsic disorder. He obtained his PhD from Moscow Institute of Physics and Technology and D.Sc. from the Institute of Experimental and Theoretical Biophysics, Russian Academy of Sciences. Since 2010, Professor Uversky has worked at University of South Florida, where he works on various aspects of protein intrinsic disorder phenomenon and analysis of protein folding and misfolding processes. He has authored over 1250 scientific publications and edited several books and book series on protein structure, function, folding, misfolding, and intrinsic disorder. He also servs as an editor in a number of scientific journals.

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