Overview

These comprehensive, up-to-date handbooks are designed for those scientists engaged in the computer analysis of sequence data who want hands-on help in using the most important commercial software available, but simply do not have the time to become computer experts. The expert authors guide you through the programs with easy-to-follow, step-by-step instructions. The topics covered include translations of sequences, sequence alignment, phylogenetic trees, analysis of RNA secondary structure, database searching, submission of data to EMBL/GenBank/DDBJ/etc., maintaining sequence projects, and using patterns to analyze protein sequences. Many chapters have been written by world-class authorities in the field, among them R. Staden, M. Gribskov, D. Higgins, W. Pearson, M. Zuker, and G. Barton. Each volume shares five essential chapters concerning the analysis of sequence data, the FASTA program, converting between sequence formats, obtaining software via INTERNET, and the submission of nucleotide sequence data. Part I covers GCG, MicroGenie, PC/GENE, and FASTA programs. Part II covers Staden and Staden Plus, DNA Strider, FASTA, and MacVector programs.

Full Product Details

Author:   Annette M. Griffin ,  Hugh G. Griffin
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   1994 ed.
Volume:   24
Dimensions:   Width: 14.80cm , Height: 2.10cm , Length: 21.00cm
Weight:   1.120kg
ISBN:  

9780896032460

ISBN 10:   0896032469
Pages:   372
Publication Date:   23 February 1994
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
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Table of Contents

Computer Analysis of Sequence Data.- GCG: Fragment Assembly Programs.- GCG: Drawing Linear Restriction Maps.- GCG: Drawing Circular Restriction Maps.- GCG: Displaying Restriction Sites and Possible Translations in a DNA Sequence.- GCG: Assembly of Sequences into New Sequence Constructs.- GCG: Comparison of Sequences.- GCG: Production of Multiple Sequence Alignment.- GCG: Database Searching.- GCG: Pattern Recognition.- GCG: Translation of DNA Sequence.- GCG: Analysis of Protein Sequences.- GCG: The Analysis of RNA Secondary Structure.- GCG: Preparing Sequence Data for Publication.- MicroGenie: Introduction and Restriction Enzyme Analysis.- MIicroGenie: Shotgun DNA Sequencing.- MicroGenie: Translation.- MicroGenie: Protein Analysis.- MicroGenie: Homology Searches.- PC/GENE: Sequence Entry and Assembly.- PC/GENE: Restriction Enzyme Analysis.- PC/GENE: Translation and Searches for Protein Coding Regions.- PC/GENE: Sequence Comparisons and Homologies.- PC/GENE: Database Searches.- PC/GENE: Searches for Functional Sites in Nucleic Acids and Proteins.- Using the FASTA Program to Search Protein and DNA Sequence Databases.- Converting Between Sequence Formats.- Obtaining Software via INTERNET.- Submission of Nucleotide Sequence Data to EMBL/GenBank/DDBJ.

Reviews

...the detailed program recipes...will provide a useful adjunct to user manuals.-Nature

...the detailed program recipes...will provide a useful adjunct to user manuals. - Nature

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