Overview
Cell Death, Part D, Volume 209 explores the latest advances in the mechanisms, regulation, and significance of cell death in health and disease. Covering diverse topics such as apoptosis, necrosis, autophagy, and emerging pathways, this volume presents chapters on Utilizing FLAMBE to study the structure-function relationship and regulation of monomeric BAX activation in solution, Sensitive detection of Lysosomal Membrane Permeabilization using the Galectin Puncta Assay, Assessing the activity of caspase-activated pannexin-1 channels by flow cytometry, In vitro culture of intestinal organoids for cell death assessments, Optimized Strategies for Necroptosis Induction and Evaluation, and more. Additional sections cover Ferroptosis induction via genetic approaches - CRISPR/Cas9-based disruption on key anti-ferroptotic genes, Reprogramming T cell fate through antibody-mediated galectin-1 blockade, 3D bioluminescence imaging assays for measuring in vitro CAR T cell cytotoxicity, The heat-ramp method to study regulated cell death in the pathogenic yeast Cryptococcus neoformans, High throughput assessment of cellular viability, and High-Throughput Screening for Cell Death Inducers and Inhibitors. This book will serve as a valuable resource for researchers, clinicians, and students interested in understanding cellular processes and their implications for therapy and diagnostics.
Full Product Details
Author: Lorenzo Galluzzi (Assistant Professor of Cell Biology in Radiation Oncology, Department of Radiation Oncology, Weill Cornell Medical College, NY, USA) ,
Manuel Beltrán Visiedo ,
Emma Guilbaud ,
Ruth Soler-Agesta
Publisher: Elsevier Science Publishing Co Inc
Imprint: Academic Press Inc
Weight: 0.450kg
ISBN: 9780443429538
ISBN 10: 0443429537
Pages: 318
Publication Date: 01 September 2026
Audience:
Professional and scholarly
,
Professional & Vocational
Format: Hardback
Publisher's Status: Forthcoming
Availability: Not yet available
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.
Author Information
Lorenzo Galluzzi is Assistant Professor of Cell Biology in Radiation Oncology at the Department of Radiation Oncology of the Weill Cornell Medical College, Honorary Assistant Professor Adjunct with the Department of Dermatology of the Yale School of Medicine, Honorary Associate Professor with the Faculty of Medicine of the University of Paris, and Faculty Member with the Graduate School of Biomedical Sciences and Biotechnology of the University of Ferrara, the Graduate School of Pharmacological Sciences of the University of Padova, and the Graduate School of Network Oncology and Precision Medicine of the University of Rome “La Sapienza. Moreover, he is Associate Director of the European Academy for Tumor Immunology and Founding Member of the European Research Institute for Integrated Cellular Pathology. Galluzzi is best known for major experimental and conceptual contributions to the fields of cell death, autophagy, tumor metabolism and tumor immunology. He has published over 450 articles in international peer-reviewed journals and is the Editor-in-Chief of four journals: OncoImmunology (which he co-founded in 2011), International Review of Cell and Molecular Biology, Methods in Cell biology, and Molecular and Cellular Oncology (which he co-founded in 2013). Additionally, he serves as Founding Editor for Microbial Cell and Cell Stress, and Associate Editor for Cell Death and Disease, Pharmacological Research and iScience.
