Xenotransplantation: Basic Research and Clinical Applications

Author:   Jeffrey L. Platt
Publisher:   Humana Press Inc.
Edition:   Softcover reprint of hardcover 1st ed. 2002
ISBN:  

9781617371271


Pages:   270
Publication Date:   05 November 2010
Format:   Paperback
Availability:   Out of stock   Availability explained
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Xenotransplantation: Basic Research and Clinical Applications


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Overview

Internationally recognized scientists, clinicians, and technologists review and explain the fundamental molecular and cellular biology that has been applied to the emerging field of transplant immunology and xenotransplantation, and what impact these advances might optimally have on medicine and science. The authoritative experts writing here-many of whom made the basic discoveries underlying the recent advances-examine the biological and immunological hurdles to xenotransplantation, illuminating how the immune system interacts with the xenograft and laying a practical foundation for the use of genetic engineering and animal transplants in the treatment of human disease.

Full Product Details

Author:   Jeffrey L. Platt
Publisher:   Humana Press Inc.
Imprint:   Humana Press Inc.
Edition:   Softcover reprint of hardcover 1st ed. 2002
Dimensions:   Width: 15.20cm , Height: 1.60cm , Length: 22.90cm
Weight:   0.421kg
ISBN:  

9781617371271


ISBN 10:   1617371270
Pages:   270
Publication Date:   05 November 2010
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

1 Molecular and Cellular Hurdles to Xenotransplantation.- 2 Pathological Responses to Xenotransplantation.- 3 Natural Xenoreactive Antibodies.- 4 Specificity of Xenoreactive Natural Antibodies.- 5 Biophysical Properties of Xenoreactive Natural Antibodies.- 6 The Origin of Xenoreactive Natural Antibodies.- 7 Synthesis of Carbohydrate Antigens Recognized by Xenoreactive Antibodies.- 8 The Complement Barrier to Xenotransplantation.- 9 Defects and Amplification of Costimulation Across the Species.- 10 Antibody-Dependent Effects on Cellular Immunity.- 11 Disordered Regulation of Coagulation and Platelet Activation in Xenotransplantation.- 12 Current Applications of Cellular Xenografts.

Reviews

"""This book provides a useful and concise review of the current status of xenotransplantion and introduces the reader to the remaining required developments before effective implementation of xenotransplantation can occur...The editor and authors are recognized authorities in the field of xenotransplantation and this book is an important addition to existing literature on this topic"" - Doody's Health Sciences Book Review Journal"


This book provides a useful and concise review of the current status of xenotransplantion and introduces the reader to the remaining required developments before effective implementation of xenotransplantation can occur...The editor and authors are recognized authorities in the field of xenotransplantation and this book is an important addition to existing literature on this topic - Doody's Health Sciences Book Review Journal


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