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Vitex negundo: A Multifaceted Medicinal Plant for Healthcare"" highlights this ethnobotanically important plant's various therapeutic uses. Vitex negundo has several pharmacological effects due to its bioactive phytochemicals, including flavonoids, essential oils, terpenoids, and lignans. Anti-inflammatory, antioxidant, antibacterial, analgesic, antipyretic, anticancer, and hepatoprotective characteristics are its main effects.Traditional medicine uses this plant to treat bronchitis, asthma, rheumatism, pain, fever, microbiological infections, and snakebites. Modern research confirms these traditional uses and shows that Vitex negundo modulates inflammation, oxidative stress, and tumor suppression. Its ability to affect signaling pathways including NF-κB, MAPK, and apoptosis makes it a promising choice for integrative medicine and pharmaceutical research.

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