Overview

This reference offers detailed descriptions of the interaction of viruses with human and animal haematopoietic cells, examines the role of viruses in human disease and important animal models, and elucidates the relationship of the immune reponse both in restricting infections and mediating organ damage. Supplying rigorous, focussed discussions which should be of benefit to both clinicians and basic scientists, Viruses and Bone Marrow : gives a general overview of viral infection in haematopoietic cells, including immune response and pathological mechanisms; describes human parvovirus and feline panleukopenia virus; presents the latest information on Epstein-Barr virus and cytomegalovirus; indicates the role of hepatitis viruses and flaviviruses in cytopenias; highlights HIV, Friend leukaemia virus, and feline leukaemia virus; reviews the use of viruses as molecular tools in gene therapy; and more. With over 1300 literature citations, tables, figures, and micrographs, Viruses and Bone Marrow is intended as a resource for haematologists, oncologists, microbiologists, virologists, infectious disease specialists, cell biologists, and graduate and medical school students in these disciplines.

Full Product Details

Author:   Neal Young (Clin-HEMAT, Bethesda, Maryland, USA)
Publisher:   Taylor & Francis Inc
Imprint:   CRC Press Inc
Volume:   16
Dimensions:   Width: 21.60cm , Height: 2.80cm , Length: 27.90cm
Weight:   0.816kg
ISBN:  

9780824788339

ISBN 10:   0824788338
Pages:   416
Publication Date:   23 March 1993
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Awaiting stock  

Table of Contents

Part 1 General aspects of virus infection of haematopoietic cells: mechanisms of viral pathogenesis, Raymond M. Welsh and Hugh I. McFarland; immune response to viral infection, Caroline I.B. Kurtz and Robert S. Fujinami. Part 2 Parvoviruses: B19 parvoviruses, Neal S. Young; feline panleukopenia virus, Gary Kurtzman. Part 3 Herpesviruses: Epstein-Barr virus, Bruce G. Baranski and Ian T. Magrath; human cytomegalovirus, Stephen St Jeor and Jaroslaw P. Maciejewski. Part 4 Flaviviruses: Dengue virus and haematopoiesis, Stephen J. Rosenfeld et al; hepatitis viruses and bone marrow depression, Pascal Bouffard and Jerome B. Zeldis. Part 5 Retroviruses: human immunodeficiency virus and the bone marrow, Jerry L. Spivak and Barbara Potts; friend spleen focus-forming virus, Sandra K. Ruscetti; feline leukaemia virus, Janis L. Abkowitz and Michael L. Linenberger. Part 6 Viruses as vectors for gene therapy: viruses as molecular tools, Arthur W. Nienhuis et al.

Reviews

. . .This excellent book will be of value both to those working at the laboratory bench and to those at the patient's bedside. ---The New England Journal of Medicine

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