Overview
Currently,there is no single source that permitscomparisonof the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our parti- lar system,missing outon theopportunityto de neunifyingthemesin viralgenome replication or bene t from the advances in other systems. For example, extraor- nary biologicaland experimentalparadigmsthat have been established overthe past 5 years for the DNA replication systems of bacteriophage T4 will likely be of great value to anyone interested in studying a replisome from any virus. These studies could easily go unnoticed by animal RNA and DNA virologists. It is our hope that this monograph will cross-fertilize and invigorate the eld, as well as encourage students into this area of research. The monograph has been divided into eight parts. Chapters appearing in Parts I-VI are intended to compare and contrast the replication and/or transcription processes and corresponding ""players"" of the indicated family of viruses. We are interested in the sequence of events that lead to production of mRNA and progeny genomes as well as the cis-acting elements and trans-acting factors and enzymes (viral and cellular) that are required for these processes. Chapters appearing in Part VII are - tended to providea more biochemical and biophysicalperspective of the replication and/ortranscriptionprocess. Chaptersappearingin Part VIII are intendedto provide a practical perspective on viral replication and its inhibition.
Full Product Details
Author: Craig E. Cameron ,
Matthias Gotte ,
Kevin Raney
Publisher: Springer-Verlag New York Inc.
Imprint: Springer-Verlag New York Inc.
Edition: 2009 ed.
Dimensions:
Width: 15.50cm
, Height: 3.40cm
, Length: 23.50cm
Weight: 0.991kg
ISBN: 9781489984685
ISBN 10: 1489984682
Pages: 636
Publication Date: 03 December 2014
Audience:
College/higher education
,
Postgraduate, Research & Scholarly
Format: Paperback
Publisher's Status: Active
Availability: Manufactured on demand
We will order this item for you from a manufactured on demand supplier.
Reviews
From the reviews: Viruses are primarily classified by the structure of their genomes. ... they can be split into either DNA or RNA, single- or double-stranded, there is great diversity in the means by which their genomes are replicated. ... the book describes the replication strategies of, with a couple of exceptions, each of the major viral groups. ... I recommend this title to all those interested in viral replication. (Christopher Ring, Microbiology Today, November, 2009)
From the reviews: Viruses are primarily classified by the structure of their genomes. ... they can be split into either DNA or RNA, single- or double-stranded, there is great diversity in the means by which their genomes are replicated. ... the book describes the replication strategies of, with a couple of exceptions, each of the major viral groups. ... I recommend this title to all those interested in viral replication. (Christopher Ring, Microbiology Today, November, 2009)
From the reviews: Viruses are primarily classified by the structure of their genomes. ... they can be split into either DNA or RNA, single- or double-stranded, there is great diversity in the means by which their genomes are replicated. ... the book describes the replication strategies of, with a couple of exceptions, each of the major viral groups. ... I recommend this title to all those interested in viral replication. (Christopher Ring, Microbiology Today, November, 2009)
