Overview

The field of angiogenesis is one of the most exciting fields in contemporary biomedical research. Angiogenesis in the healthy adult is primarily associated with pathological conditions such as tumor growth, inflammation, ischemia, and retinopathies. Physiological angiogenesis in the healthy adult is restricted to the organs of the female reproductive system where it occurs cyclically as well as during pregnancy. The importance of vascular morphogenetic events in the female reproductive system is increasingly being recognized. For example, it has a vital role in normal ovarian function, endometriosis and placental function as well as being important in reproductive tumors of the mammary gland, ovary and uterus. The insights gained from studying this system have a more general interest too since they help shed light on the fundamental characteristics and components involved in the formation of the vascular system and blood vessels during development, and during tumorigenesis. This is the first book that reviews and presents recent advances in the emerging field of reproductive vascular biology. It is divided into four parts reflecting the four female reproductive organs (breast, ovary, uterus, and placenta) and the authors cover both the basic biological processes involved and also stress their clinical significance. The book will interest vascular and reproductive biologists as well as cell and developmental biologists interested in angiogenesis and vasculogenesis.

Full Product Details

Author:   Hellmut G. Augustin ,  M. Luisa Iruela-Arispe ,  Peter A.W. Rogers ,  Stephen K. Smithe
Publisher:   Birkhauser Boston Inc
Imprint:   Birkhauser Boston Inc
Dimensions:   Width: 17.80cm , Height: 2.50cm , Length: 25.40cm
Weight:   0.848kg
ISBN:  

9780817642211

ISBN 10:   0817642218
Pages:   333
Publication Date:   29 June 2001
Audience:   College/higher education ,  Professional and scholarly ,  Postgraduate, Research & Scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

I: Vascular Morphogenesis in the Mammary Gland:.- 1. Vascular Morphogenesis in the Mammary Gland: Introduction and Overview.- 2. Growth Factor Regulation of Physiologic Angiogenesis in the Mammary Gland.- 3. The Role of Angiogenesis in Breast Cancer Progression.- 4. Angiogenesis in Mammary Tumors: Quantitation and Relation to Prognosis.- 5. Oncogenes, Anti-Oncogenes, and Genetic Regulators of Vascular Development.- II: Vascular Morphogenesis in the Ovary.- 6. Vascular Morphogenesis in the Ovary: Introduction and Overview.- 7. Growth Factors During Ovarian Angiogenesis.- 8. Vascular Endothelial Growth Factor: A Key Regulator of Physiologic Angiogenesis.- 9. Hormonal Regulation of Gonadal Angiogenesis.- 10. Angiogenesis, Vascular Imaging, and Therapeutic Approaches in Ovarian Tumors.- III: Vascular Morphogenesis in the Uterus.- 11. The Vascular System in the Endometrium: Introduction and Overview.- 12. The Clinical Relevance of Disturbances of Uterine Vascular Growth, Remodeling, and Repair.- 13. Angiogenesis in Endometriosis.- IV: Vascular Morphogenesis in the Placenta.- 14. Placental Vascular Morphogenesis: Introduction and Overview.- 15. Placental Functional Morphology.- 16. Placenta Growth Factor.- 17. Early Placental Vascular Morphogenesis.

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