Overview

In the realm of surgical pathology, specifically within regions endemic to neglected tropical diseases (NTDs), this book serves as a comprehensive reference on nonclassical vascular risk factors from an epidemiological standpoint. It addresses the often-overlooked issue of vascular damage in patients afflicted with parasitic diseases and other NTDs. Current literature primarily consists of rare individual case reports and case series for each specific disease, making this book a valuable contribution to the field. The book describes various aspects related to vascular involvement in NTDs, including parasitological, vector borne diseases and snakebite-associated vascular lesions. Although these cases and their underlying pathophysiologic mechanisms are rarely reported and remain understudied, this book describes the various nuances of surgical vascular pathology in this setting, encouraging further research in this area. Five main topics are covered: the vascular problems in patients with 1. Schistosomiasis, 2. Amebiasis, 3. Hydatidosis, 4. Lymphatic filariasis, and 5. Snakebites. This work raises awareness of these rarely reported diseases in areas where they are more common or in countries where they are imported, among physicians directly involved in the management of these cases. It serves as a guide to treatment from presentation through the various steps of patient care. The book is a reference for all professionals concerned with morbidity associated with neglected tropical diseases, particularly vascular morbidity of surgical interest, both research and clinical, in endemic and non-endemic settings. It is a valuable resource for the continuing education of health professionals working in this field. It serves as a textbook for vascular surgery fellows interested in non-classical cardiovascular risk factors leading to surgical conditions. This specific topic related to non-communicable comorbidities in diseases of parasitological interest is useful for parasitologists and public health specialists at master level and above.      

Full Product Details

Author:   Valeria Silvestri ,  Vivian Mushi ,  Billy Ngasala
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   2024 ed.
ISBN:  

9783031533525

ISBN 10:   3031533526
Pages:   116
Publication Date:   04 July 2024
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1. Introduction  Neglected tropical disease definition  Neglected tropical diseases general epidemiology  Knowledge-gap challenge: the lack of stats issue This section will provide a definition for neglected tropical diseases and their epidemiology, focusing on challenging aspects of research in this area. Specifically it will put emphasis on the lack of reliable and systematically collected statistical data for many of these conditions, and on the under-report, under-diagnosis-undertreatment of many cases, due to healthcare challenges that affect endemic regions. 2. Schistosomiasis  Epidemiology, physiopathology, clinical features, diagnostic tools, pharmacological management of schistosomiasis, outcome of patients with schistosomiasis  Vascular damage in schistosomiasis: pathophysiology  Aneurysms in schistosomiasis  Cerebrovascular diseases in schistosomiasis This section will will analyse the mechanisms by which the trematode’s eggs can be responsible of arterial direct or indirect damage. In the third and fourth section aneurysms occurring in schistosomiasis and stroke occurring in the same condition will be considered. 3. Hydatidosis  Epidemiology, physiopathology, clinical features, diagnostic tools, pharmacological management of hydatidosis, outcome of patients with hydatidosis  Vascular damage in hydatidosis  Aneurysm in hydatidosis  Acute limb ischemia in hydatidosis After introducing hydatidosis from a parasitological perspective, there will be a section related to specific pathophysiology of vascular damage in hydatidiasis. A section related to aneurysm in patients caused by echinococcal invasion of the artery will follow. A section on embolization of hydatid cyst material manifesting with ischemia or reached district will be provided. 4. Amoebiasis  Epidemiology, physiopathology, clinical features, diagnostic tools, pharmacological management of amoebiasis, outcome of patients with amoebiasis  Vascular damage in amoebiasis  Aneurysms in amoebiasis In this section we will analyse protozoa Amoeba hystolitica, and mainly concentrate on aneurysms complicating ameoebic hepatic abscess. 5. Lymphatic filariasis  Epidemiology, physiopathology, clinical features, diagnostic tools, pharmacological management of lymphatic filariasis, outcome of patients with lymphatic filariasis  Vascular damage in patients with lymphatic filariasis  Lymphangiosarcoma in patients with lymphatic filariasis This chapter will cover lymphatic damage due to filarial helminths and, more specifically for the surgical aspect of vascular damage, it will analyse the issue of lymphangiosarcoma occurring in patients affected by chronic lymphatic filariasis. 6. Tungiasis  Epidemiology, physiopathology, clinical features, diagnostic tools, pharmacological management of tungiasis, outcome of patients with tungiasis  Vascular damage in patients with tungiasis  Progression of Chronic limb ischemia in tungiasis In this chapter we will analyse a disease of entomological interest, tungiasis. From a vascular point of view, this ectoparasite could be of concern in patients with microangiopathy, like in diabetes. In diabetic patients with microangiopathy, the local damage caused by the feeding parasite, together with the impairment in mechanisms of tissue repair, and the potentially co-occurrent macroangiopathy in the form of chronic limb ischemia, could lead to the worsening of peripheral artery diseases stage, leading to amputation or death. 7. Snakebites envenomation  Epidemiology, physiopathology, clinical features, diagnostic tools, pharmacological management of snakebites envenomation, outcome of patients after snakebite envenomation  Vascular damage after snakebite envenomation  Arterial rupture after snakebite envenomation  Compartment syndrome after snakebite envenomation Snakebite envenomation was recently included among the list of neglected tropical conditions. Both the mechanical lesions at bite site and the local and the systemic effects of venom can cause vascular damage in the victim.

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Author Information

Valeria Silvestri is an Italian physician who specialized in Vascular and Endovascular Surgery at the University of Perugia in 2014. She holds a PhD in Cardiovascular Pathology and Imaging, achieved at La Sapienza University in Rome in 2018.  Her strong interest in  the  medical  scenario of  south  Saharan  setting motivated  her to achieve a Master of Science in Parasitology and  Medical  Entomology at   Muhimbili University of  Health  and  Allied  Science, in Tanzania. In the multi-disciplinary and scientifically fervid environment of the department of Parasitology at MUHAS, under the guide of Prof. Billy Ngasala, she had the opportunity to contribute with her expertise in vascular diseases to the research that inspired and documented this book.       Vivian Mushi has a BSc in Microbiology (Hons) and MSc in Tropical Disease Control. She is an Assistant Lecturer and Junior Researcher in the Department of Parasitology and Medical Entomology. She teaches courses on Protozoology, Helminthology, and Medical Entomology. Her research interests are focused on the control of Neglected Tropical Diseases (NTDs) in vulnerable populations by implementing sustainable interventions that reduce NTD transmission and their morbidities. Currently, she is a PhD candidate working on Onchocerciasis, specifically on Onchocerciasis-Associated Epilepsy (OAE) in Mahenge. She is a member of various communities such as Epilepsy Pathway Innovation in Africa (EPInA), the Royal Society of Tropical Medicine and Hygiene (RSTMH), Community of Young Research Peers in Tanzania, Women in Parasitology (WiP), and Women in Malaria (WiM). Billy Ngasala is a Professor of Parasitology and Medical Entomology and Head of the Department of Medical Parasitology and Medical Entomology, at Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. Prof. Ngasala is a member of the American Society of Tropical Medicine and Hygiene.  

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