Overview

This volume provides a practical guide providing step-by-step methods and protocols on vaccine development and production. Divided into three volumes, Volume 3: Resources for Vaccine Development guides readers through chapters on vaccine adjuvants, vaccine vectors, production, vaccine delivery systems, vaccine bioinformatics, vaccine regulation, and intellectual property. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols. Authoritative and practical, Vaccine Design: Methods and Protocols, Second Edition, Volume 3: Resources for Vaccine Development aims to be a useful practical guide to researchers to help further their study in this field.

Full Product Details

Author:   Sunil Thomas
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   2nd ed. 2022
Volume:   2412
Weight:   1.060kg
ISBN:  

9781071618943

ISBN 10:   1071618946
Pages:   546
Publication Date:   18 December 2022
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

PART I TRENDS IN VACCINE DEVELOPMENT 1. Artificial Intelligence for Vaccine Design Peter McCaffrey   2. Progress in the Development of Structure-Based Vaccines Sunil Thomas and Ann Abraham   3. Polymer-Peptide Conjugate Vaccine for Oral Immunization Mohammad Omer Faruck, Mariusz Skwarczynski, and Istvan Toth   4. An update on “Reverse Vaccinology”: The Pathway from Genomes and Epitope Predictions to Tailored, Recombinant Vaccines Marcin Michalik, Bardya Djahanshiri, Jack C. Leo, and Dirk Linke   PART II VACCINE VECTORS AND PRODUCTION SYSTEM 5. Phage T7 as a Potential Platform for Vaccine Development Chuan Loo Wong, Chean Yeah Yong and Khai Wooi Lee   6. Plant-based Systems for Vaccine Production Mattia Santoni, Elisa Gecchele, Roberta Zampieri, and Linda Avesani   7. Production of a Hepatitis E Vaccine Candidate Using the Pichia pastoris Expression System Jyoti Gupta, Amit Kumar, and Milan Surjit   PART III VACCINE ADJUVANTS 8. Developments in Vaccine Adjuvants Farrhana Ziana Firdaus, Mariusz Skwarczynski, and Istvan Toth   9. Adjuvants: Engineering Protective Immune Responses in Human and Veterinary Vaccines Bassel Akache, Felicity C. Stark, Gerard Agbayani, Tyler M. Renner and Michael J. McCluskie   10. Cationic Nanostructures as Adjuvants for Vaccines                                                                                                      Ana Maria Carmona-Ribeiro, Beatriz Ideriha Mathiazzi, and Yunys Pérez-Betancourt   11. Emulsion Adjuvants for Use in Veterinary Vaccines Rachel Madera, Yulia Burakova, and Jishu Shi   12. Generation of a Liposomal Vaccine Adjuvant Based on Sulfated S-lactosylarchaeol (SLA) Glycolipids Bassel Akache, Yimei Jia, Vandana Chandan, Lise Deschatelets and Michael J. McCluskie   13. Glucan particles: choosing the appropriate size to use as a vaccine adjuvant Mariana Colaço, João Panão Costa, and Olga Borges   PART IV VACCINE DELIVERY SYSTEMS       14. Use of Optical In Vivo Imaging to Monitor and Optimize Delivery of Novel Plasmid-Launched Live-Attenuated Vaccines Sapna Sharma and Kai Dallmeier   15. Liposomes for the Delivery of Lipopeptide Vaccines Jieru Yang, Armira Azuar, Istvan Toth, and Mariusz Skwarczynski   16. Current Prospects in Peptide-Based Subunit Nanovaccines Prashamsa Koirala, Sahra Bashiri, Istvan Toth, and Mariusz Skwarczynski   17. Design and Synthesis of Protein-based Nanocapsule Vaccines Ivana Skakic, Jasmine. E. Francis, and Peter. M. Smooker   18. Design and Preparation of Solid Lipid Nanoparticle (SLN) Mediated DNA Vaccines Jasmine. E. Francis, Ivana Skakic, and Peter. M. Smooker   19. Nano-Particulate Platforms for Vaccine Delivery to Enhance Antigen-Specific CD8+ T Cell Response Jhanvi Sharma, Carcia S. Carson, Trevor Douglas, John T. Wilson, and Sebastian Joyce   20. PilVax: A Novel Platform for the Development of Mucosal Vaccines Catherine (Jia-Yun) Tsai, Jacelyn M.S. Loh, and Thomas Proft   PART V VACCINE BIOINFORMATICS 21. Bioinformatic Techniques for Vaccine Development: Epitope Prediction and Structural Vaccinology Peter McCaffrey   22. Immunoinformatic Approaches for Vaccine Designing for Pathogens with Unclear Pathogenesis Naina Arora, Anand K. Keshri, Rimanpreet Kaur, Suraj Singh Rawat, and Amit Prasad   23. In silico Identification of the B-cell and T-cell Epitopes of the Antigenic Proteins of Staphylococcus aureus for Potential Vaccines Sunil Thomas and Irini Doytchinova   24. Computational Mining and Characterization of Hypothetical Proteins of Mycobacterium Bovis towards the Identification of Probable Vaccine Candidates Bhaskar Ganguly   25. Recombinant Vaccine Design against Clostridium Spp. Toxins using Immunoinformatics Tools Rafael Rodrigues Rodrigues, Marcos Roberto Alves Ferreira, Frederico Schmitt Kremer, Rafael Amaral Donassolo, Clóvis Moreira Júnior, Mariliana Luiza Ferreira Alves, and Fabricio Rochedo Conceição   26. Searching Epitope-based Vaccines Using Bioinformatic Studies Marlet Martínez-Archundia, G Lizbeth Ramírez-Salinas, Jazmin García-Machorro and José Correa-Basurto   PART VI VACCINE SAFETY AND REGULATION 27. The Regulatory Evaluation of Vaccines for Human Use Norman W. Baylor   PART VII VACCINE INTELLECTUAL PROPERTY 28. Intellectual Property Rights and Vaccines Penny Gilbert, Richard Fawcett, Joel Coles, and William Hillson   29. Vaccine Intellectual Property Ana Santos Rutschman, Joshua D. Sarnoff, and Timothy L. Wiemken   PART VIII PATHWAYS TO VACCINE COMMERCIALIZATION 30. Resources for Starting a Company Ann Abraham, Jude Mathew, and Sunil Thomas    

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