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Author:   Holger Barth
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   1st ed. 2017
Volume:   406
Weight:   5.207kg
ISBN:  

9783319588919

ISBN 10:   3319588915
Pages:   256
Publication Date:   19 December 2017
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Manufactured on demand  
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Table of Contents

Two feet on the membrane: uptake of clostridial neurotoxins.- Receptors and binding structures for Clostridium difficile Toxins A and B.- Cell entry of C3 exoenzyme from Clostridium botulinum.- Receptor-binding and up-take of binary actin-ADP-ribosylating toxins.- Clostridial Binary Toxins: Basic Understandings that Include Cell-Surface Binding and an Internal “Coup de Grace”.- Host cell chaperones Hsp70/Hsp90 and peptidyl-prolyl cis/trans isomerases are required for the membrane translocation of bacterial ADP-ribosylating toxins.- Multivalent Inhibitors of Channel-Forming Bacterial Toxins.- Toxin Transport by A-B Type of Toxins in Eukaryotic Target Cells and its inhibition by Positively Charged Heterocyclic Molecules.

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Author Information

Holger Barth Institute of Pharmacology and Toxicology, University of Ulm Medical Center, Albert-Einstein-Allee 11, 89081 Ulm, Germany, e-mail: holger.barth@uni-ulm.de

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