Untangling the Double Helix: DNA Entanglement and the Action of the DNA Topoisomerases
Author:   James C. Wang
Publisher:   Cold Spring Harbor Laboratory Press,U.S.
ISBN:  

9780879698638


Pages:   233
Publication Date:   10 April 2009
Format:   Hardback
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

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Untangling the Double Helix: DNA Entanglement and the Action of the DNA Topoisomerases


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Author:   James C. Wang
Publisher:   Cold Spring Harbor Laboratory Press,U.S.
Imprint:   Cold Spring Harbor Laboratory Press,U.S.
Dimensions:   Width: 16.30cm , Height: 1.90cm , Length: 22.10cm
Weight:   0.567kg
ISBN:  

9780879698638


ISBN 10:   0879698632
Pages:   233
Publication Date:   10 April 2009
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock   Availability explained
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Preface 1. An Insuperable Problem 2. Nature's Solutions: The DNA Topoisomerases 3. Breaking a DNA Strand and Holding on to the Broken Ends 4. A Magic Swivel 5. Moving One DNA Double Helix through Another 6. Real-Time Viewing of the DNA Topoisomerases in Action 7. Manifestations of DNA Entanglement: Replication and Recombination 8. Manifestations of DNA Entanglement: Gene Expression 9. Beyond DNA Entanglement: New Twists on an Old Theme 10. From Nature's Battlefields to the Clinical Wards Appendices 1. Identification of the Covalent Intermediates in Topoisomerase-Catalyzed Reactions 2. Catalysis of DNA Breakage and Rejoining by DNA Topoisomerases Index

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