Unlocking Protein Structure-Function Relationships: Computational and Experimental Approaches and Applications

Author:   Avia Rosenhouse-Dantsker
Publisher:   Springer Nature Switzerland AG
ISBN:  

9783032075109


Pages:   398
Publication Date:   07 February 2026
Format:   Hardback
Availability:   Not yet available   Availability explained
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Unlocking Protein Structure-Function Relationships: Computational and Experimental Approaches and Applications


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Author:   Avia Rosenhouse-Dantsker
Publisher:   Springer Nature Switzerland AG
Imprint:   Springer Nature Switzerland AG
ISBN:  

9783032075109


ISBN 10:   3032075106
Pages:   398
Publication Date:   07 February 2026
Audience:   Professional and scholarly ,  College/higher education ,  Professional & Vocational ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   Not yet available   Availability explained
This item is yet to be released. You can pre-order this item and we will dispatch it to you upon its release.

Table of Contents

 Advanced computational methods in protein simulations.- Enhanced sampling and free energy calculations in protein simulations.- Design of protein structure and function.- Artificial intelligence in protein structure prediction.- Optimized methods for site identification in proteins.- Machine Learning tools for Peptide Protein Interaction Prediction.- Simulating Protein Ligand Binding with Neural Network Potentials.- Prediction of protein complex structures using protein protein interaction data.- Advances in X ray crystallography and cryo EM structural studies of protein structure and function.- Fluorescence microscopy methods for studying dynamics of fluorescent proteins in vivo.- Nanoscale fluorescence imaging of proteins.- Multiplexed protein imaging methods.- Determining protein structure by combining protein chemistry with mass spectrometry.- NMR spectroscopy techniques as a tool for characterizing the interactions in protein-protein complexes.- Electrophysiology tools in the study of ion channel proteins.

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Author Information

Dr. Rosenhouse-Dantsker’s M.Sc. and D.Sc. theses in chemistry focused on quantum theory at the interface of chemistry, physics, and mathematics. After continuing in this direction for several years as a postdoctoral fellow, she became interested in research at the interface of chemistry, biology, and medicine. Pursuing postdoctoral training at the Mount Sinai School of Medicine in New-York, she first performed computational biology research on G protein-coupled receptors and then delved into experimental research in the ion channel field. Since 2002, Dr. Rosenhouse-Dantsker’s research has focused on the modulation of potassium channels by ions, proteins, and lipids using a combination of experimental and computational approaches. Her research has been published in Nature Chemical Biology, PNAS, J Neuroscience, J Lipid Research, and JBC, among other leading journals. In 2008, Dr. Rosenhouse-Dantsker joined the University of Illinois Chicago where she is now a Clinical Associate Professor. Dr. Rosenhouse-Dantsker has co-edited two volumes on the modulation of protein function by cholesterol (Springer), and served as the editor of Cholesterol and PI(4,5)P2 in Vital Biological Functions: From Coexistence to Crosstalk (Springer).  

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