Overview

Full Product Details

Author:   Laura R. McCabe ,  Narayanan Parameswaran
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2017
Volume:   1033
Weight:   0.454kg
ISBN:  

9783319882932

ISBN 10:   3319882937
Pages:   277
Publication Date:   09 September 2018
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand  
We will order this item for you from a manufactured on demand supplier.

Table of Contents

Section I: Gut and Bone Physiology.- 1.Introduction.- 2.GI Research: Physiology and Gut Signaling to other organs.- Section II: Gut-Bone Signaling Pathways.- 3. Intestinal regulation of Calcium-Vitamin D and Regulation of Bone Physiology.- 4. GI Regulation of Incretins and Modulation of Bone.- 5.Intestinal Serotonin Regulation of Bone Physiology.- 5. Gut Microbiome and Bone Physiology.- 6. Intestinal Immune System and Regulation of Bone.- Section III: Gut Pathologies Affecting Bone Health.- 7. Stomach-Bone: Gastric Acid and Calcium Absorption.- 8. Inflammatory  Bowel Disease:  Human IBD and Mouse IBD Models.- 9. Antibiotic Use.- 10. Enteritis and Pathogens: Dysbiosis, Pediatrics and Aging.- 11. Enteritis and Pathogens: Chicken Models.- Section IV: Modulation of the Gut Microbiota to Support Bone Health.- 12. Prebiotics.- 13.- Probiotics.- 14. Germ Free Applications.

Reviews

Author Information

Laura R. McCabe, PhD is the Director of the Molecular Metabolism and Disease Program at Michigan State University. Dr. McCabe’s research focuses on understanding the mechanisms regulating bone cell (osteoblast) differentiation and bone formation. Her lab is taking an integrative approach to examine bone adaptation to diseases (such as diabetes and inflammatory bowel disease) and is working toward identifying mechanisms regulating bone formation by osteoblasts.  Approaches include examination of transcription factor activity, intracellular signaling pathway activation, stem cell lineage selection, apoptosis, metabolism and immune system contributions utilizing cell culture systems, animal models and human imaging. Dr. McCabe’s lab is also developing therapeutics to target identified mechanisms and pathways to increase bone formation.

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions