Overview

This comprehensive textbook, edited by world-renowned experts in the field, provides answers to challenges in the diagnosis and treatment of craniofacial anomalies.The book integrates basic science and clinical perspectives, creating a more unified and practical “patient centered” approach. Organized in a logical, easy-to-follow structure, this reference reviews and presents cutting-edge findings, covering the state of the art in craniosynostosis and facial clefting from molecular, genetic, cellular, tissue, organismic, and populations levels. Using standardized nomenclature and consistent terminology, Understanding Craniofacial Anomalies incorporates the recent explosion of growth in studying genetic and epigenetic etiologies of syndromes, thereby providing a unique and holistic review of this important topic.

Full Product Details

Author:   Mark P. Mooney (University of Pittsburgh, Pittsburgh, PA) ,  Michael I. Siegel (University of Pittsburgh, Pittsburgh, PA)
Publisher:   John Wiley and Sons Ltd
Imprint:   John Wiley & Sons Inc
Dimensions:   Width: 18.20cm , Height: 3.60cm , Length: 25.90cm
Weight:   1.243kg
ISBN:  

9780471387244

ISBN 10:   047138724
Pages:   583
Publication Date:   03 May 2002
Audience:   College/higher education ,  Professional and scholarly ,  Undergraduate ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Out of stock  

Table of Contents

Forward. Preface. Contributors. SECTION I: CLASSIFICATION AND TERMINOLOGY. Overview and Introduction (M. Mooney & M. Siegel). Terminology and Classification of Craniosynostosis (M. Jones). Terminology and Classification of Facial Clefting (R. Shprintzen). SECTION II: EMBRYOGENESIS AND ETIOLOGY. Craniofacial Embryogenesis: Normal Developmental Mechanisms (G. Sperber). Johnston and Bronsky. Genetic Etiologies of Craniosynostosis (E. Jabs). Genetic Etiologies of Facial Clefting (M. Marazita). Environmental Etiologies of Orofacial Clefting and Craniosynostosis (V. Shashi & T. Hart). SECTION III: ANIMAL MODELING. Animal Models and Craniosynostosis: Experimental, Congenital, and Transgenic Models (M. Mooney, et al.). Aniaml Models of Facial Clefting - Experimental, Congenital, and Transgenic (V. Diewert & S. Lozanoff). SECTION IV: CRANIAL VAULT AND CRANIAL BASE DYSMORPHOLOGY AND GROWTH DISTURBANCES. Evolutionary Changes in the Cranial Vault and Base: Establishing the Primate Form (M. Mooney, et al.). Cranial Base Dysmorphology and Growth in the Craniosynostoses (A. Burdi). Cranial Base Dysmorphology and Growth in Facial Clefting (T. Smith, et al.). Cranial Vault Morphology and Growth in Craniosynostosis (J. Richtsmeier). SECTION V: MIDFACIAL AND MANDIBULAR DYSMORPHOLOGY AND GROWTH DISTURBANCES. Evolutionary Changes in the Midface and Mandible: Establishing the Primate Form (J. Siebert & D. Swindler). Facial Dysmorphology in the Craniosynostoses: Clinical Implications (K. Vig). Midfacial and Mandibular Dysmorphology and Growth in Facial Clefting: Clinical Implications (B. Ross). SECTION VI: REGIONAL DYSMORPHOLOGY AND GROWTH DISTURBANCES. Dental Development and Anomalies in Craniosynostoses and Facial Clefting (E. Harris). Vocal Tract Anatomy and Functional Concequences in Cleft Lip/Palate and Syndromes of Craniosynostosis (S. Peterson-Falzone & P. Monoson). SECTION VII: MOLECULAR BIOLOGY STUDIES AND FUTURE DIRECTIONS. Molecular Studies of Craniosynostosis: Factors Affecting Cranial Suture Morphogenesis and Patency (L. Opperman & R. Ogle). Molecular Studies of Facial Clefting: From Mouse to Man (M. Melnick & T. Jaskoll). Molecules and Faces: What is on the Horizon? (H. Slavkin). Index.

Reviews

A very useful book...well written, amply illustrated... (Journal of Endocrine Genetics, Vol 3 No 3, 2003) This book provides an excellent introduction to craniofacial anomalies. It provides a good mix of basic science and clinical aspects and reflects the recent explosion of growth in the knowledge about the study of genetics. (Doody's) ...A very useful book... (Journal of Pediatric Endocrinology & Metabolism) ...appropriately thorough and learned summary of the state of knowledge of craniofacial evolution and embryology.... (Pediatric and Developmental Pathology, Vol. 6, 2002)

A very useful book!well written, amply illustrated! (Journal of Endocrine Genetics, Vol 3 No 3, 2003) ...provides an excellent introduction!takes different aspects of all the disciplines involved!and puts it under one title. (Doody's) ...A very useful book... (Journal of Pediatric Endocrinology & Metabolism, Vol.15, No.8, 2002) ...appropriately thorough and learned summary of the state of knowledge of craniofacial evolution and embryology... (Pediatric and Developmental Pathology, Vol. 6, 2002)

A very useful book well written, amply illustrated (Journal of Endocrine Genetics, Vol 3 No 3, 2003) ...provides an excellent introduction takes different aspects of all the disciplines involved and puts it under one title. (Doody's) ...A very useful book... (Journal of Pediatric Endocrinology & Metabolism, Vol.15, No.8, 2002) ...appropriately thorough and learned summary of the state of knowledge of craniofacial evolution and embryology... (Pediatric and Developmental Pathology, Vol. 6, 2002)

Author Information

Mark P. Mooney, Ph.D. is an Associate Professor of Oral Medicine and Pathology at the University of Pittsburgh. He has conducted research and published extensively on craniofacial anomalies for over 20 years. He also teaches health professional, graduate, and undergraduate courses in Anatomy, Physical Anthropology, and Growth and Development. Michael I. Siegel, Ph. D. is a Professor of Physical Anthropology at the University of Pittsburgh. For over 30 years he has taught research design courses as well as Anatomy, Physical Anthropology and Human Biology. He has conducted research and published extensively on the topic of craniofacial anomalies.

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