UHMWPE Biomaterials Handbook: Ultra High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices

Author:   Steven M. Kurtz, Ph.D. (Director, Implant Research Center and Associate Professor, Drexel University; Research Assistant Professor, Thomas Jefferson University, Philadelphia, PA, USA)
Publisher:   Elsevier Science Publishing Co Inc
Edition:   2nd edition
ISBN:  

9780123747211


Pages:   568
Publication Date:   26 June 2009
Replaced By:   9780323354011
Format:   Hardback
Availability:   Awaiting stock   Availability explained


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UHMWPE Biomaterials Handbook: Ultra High Molecular Weight Polyethylene in Total Joint Replacement and Medical Devices


Overview

UHMWPE Biomaterials Handbook describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This material is currently used in 1.4 million patients around the world every year for use in the hip, knee, upper extremities, and spine. Since the publication of the 1st edition there have been major advances in the development and clinical adoption of highly crosslinked UHMWPE for hip and knee replacement. There has also been a major international effort to introduce Vitamin E stabilized UHMWPE for patients. The accumulated knowledge on these two classes of materials are a key feature of the 2nd edition, along with an additional 19 additional chapters providing coverage of the key engineering aspects (biomechanical and materials science) and clinical/biological performance of UHMWPE, providing a more complete reference for industrial and academic materials specialists, and for surgeons and clinicians who require an understanding of the biomaterials properties of UHMWPE to work successfully on patient applications.

Full Product Details

Author:   Steven M. Kurtz, Ph.D. (Director, Implant Research Center and Associate Professor, Drexel University; Research Assistant Professor, Thomas Jefferson University, Philadelphia, PA, USA)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   2nd edition
Dimensions:   Width: 21.60cm , Height: 3.30cm , Length: 27.60cm
Weight:   1.920kg
ISBN:  

9780123747211


ISBN 10:   012374721
Pages:   568
Publication Date:   26 June 2009
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9780323354011
Format:   Hardback
Publisher's Status:   Out of Print
Availability:   Awaiting stock   Availability explained

Table of Contents

A Primer on UHMWPE From Ethylene Gas to UHMWPE Component: The Process of Producing Orthopedic Implants Packaging and Sterilization of UHMWPE The Origins of UHMWPE in Total Hip Arthroplasty Clinical Performance of UHMWPE in Hip Replacements Contemporary Total Hip Arthroplasty: Hard-on-Hard Bearings and Highly Crosslinked UHMWPE Origins and Adaptations of UHMWPE for Knee Replacements Clinical Performance of UHMWPE in Knee Replacements Clinical Performance of UHMWPE in Shoulder Replacements Clinical Performance of UHMWPE in Elbow Replacements Applications of UHMWPE in Total Ankle Replacements Clinical Performance of UHMWPE in the Spine Highly Crosslinked and Melted UHMWPE Highly Crosslinked and Annealed UHMWPE Highly Crosslinked UHMWPE Doped with Vitamin E Vitamin E-Blended UHMWPE Biomaterials Composite UHMWPE Biomaterials and Fibers UHMWPE/ Hyaluronan Microcomposite Biomaterials High Pressure Crystallized UHMWPEs Compendium of Highly Crosslinked UHMWPEs Mechanisms of Crosslinking, Oxidative Degradation and Stabilisation of UHMWPE In Vivo Oxidation of UHMWPE Pathophysiologic Reactions to UHMWPE Wear Particles Characterization of Physical, Chemical, and Mechanical Properties of UHMWPE Tribological Assessment of UHMWPE in the Hip Tribological Assessment of UHMWPE in the Knee Characterisation of UHMWPE Wear Particles Clinical Surveillance of UHMWPE Using Radiographic Methods ESR Insights into Macro Radicals in UHMWPE Fatigue and Fracture of UHMWPE Development and Application of the Notched Tensile Test to UHMWPE Development and Application of the Small Punch Test to UHMWPE Nano- and Micro-Indentation Testing of UHMWPE MicroCT Analysis of Wear and Damage in UHMWPE Computer Modeling and Simulation of UHMWPE

Reviews

The UHMWPE Handbook is a comprehensive yet concise presentation of the important role that polyethylene has played and continues to play in the treatment armamentarium of the orthopaedic surgeon. - Joshua J. Jacobs, MD, Rush University Medical Center, Chicago, IL


Journal of Bone and Joint Surgery <br>The UHMWPE Handbook is a comprehensive yet concise presentation of the important role that polyethylene has played and continues to play in the treatment armamentarium of the orthopaedic surgeon. The comprehensiveness of this volume is evidenced by the broad range of topics addressed: from the history of the clinical introduction and clinical performance of ultra-high molecular weight polyethylene in hip and knee arthroplasty to the complexities of polyethylene synthesis and processing, resin nomenclature, material degradation, analytic modeling, biomechanical and structural characterization, and currently available highly cross-linked products. Even though each one of these topics could not be dealt with in great depth, the breadth of the subject matter gives the reader an excellent overview of the field that will stimulate further reading and research. Portions of this book will be of great interest to orthopaedic residents and orthopaedic surgeons, providing them with a basic framework to understand the performance of ultra-high molecular weight polyethylene in a variety of clinical settings, including arthroplasty of the hip, knee, shoulder, and disc. This book should be read by individuals who are involved in clinical and basic research concerning polyethylene performance as well as by biomedical engineering trainees who intend to pursue a career in the orthopaedic device industry. The author and his colleagues are to be commended for compiling this information and producing an authoritative and useful resource for our specialty. - Joshua J. Jacobs, MD, Rush University Medical Center, Chicago, Illinois


Author Information

Dr. Kurtz has been researching ultra-high molecular weight polyehtylene(UHMWPE) for use in orthopedics for over 10 years. He has published dozens of papers and several book chapters related to UHMWPE used in joint replacement. He has pioneered the development of new test methods for the material in orthopedics. Dr. Kurtz has authored national and international standards for medical upgrade UHMWPE.As a principle engineer at Exponent, an international engineering and scientific consulting company, his research on UHMWPE is supported by several major orthopedic manufacturers. He has funding from the National Institutes for Health to stdy UHMWPE changes after implanatation in the body, as well as to develop new computer-based tools to predict the performance of new UHMWPE materials.Dr. Kurtz is the Director of an orthopedic implant retrieval program in Philadelphia which is affiliated with Drexel University and Thomas Jefferson University. He teaches classes on the performance of orthopedic polymers (including UHMWPE) at Drexel, Temple, and Princeton Universities.

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