Ubiquitin Chains: Degradation and Beyond
Author:   Arnab De
Publisher:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2015
ISBN:  

9783319385341


Pages:   103
Publication Date:   09 October 2016
Format:   Paperback
Availability:   Manufactured on demand   Availability explained
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Ubiquitin Chains: Degradation and Beyond


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Author:   Arnab De
Publisher:   Springer International Publishing AG
Imprint:   Springer International Publishing AG
Edition:   Softcover reprint of the original 1st ed. 2015
Weight:   0.454kg
ISBN:  

9783319385341


ISBN 10:   3319385348
Pages:   103
Publication Date:   09 October 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   Manufactured on demand   Availability explained
We will order this item for you from a manufactured on demand supplier.

Table of Contents

1 Immune homeostasis: Activation and Downregulation of NF-κB.- 2 Regulation of NF-κB signaling by regulatory ubiquitination: specific pathways and A20.- 3 The deubiquitinase activity of A20 is dispensable for its role in NF-κB signaling.- 4 Perspectives on regulatory ubiquitination.

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Dr. Arnab De received his PhD from the Department of Microbiology & Immunology at Columbia University. During his PhD, he developed transgenic mice to study the mechanism of action of a critical tumor-suppressor called A20. He is also well known for having developed peptide-based prodrugs as therapeutics for diabetes. His work has been reported by the media, and has resulted in multiple patents and publications in peer reviewed journals. He presented his findings at the American Peptide Symposium and was awarded the Young Investigator’s Award. He is the author of Application of Peptide-Based Prodrug Chemistry in Drug Development, with a foreword written by Professor Jean Martinez (Former President, European Peptide Society) and published in the series SpringerBriefs in Pharmaceutical Science & Drug Development. His research interests lie at the intersection of chemistry and medicine.  Besides biomedical research, he is also generally interested in public health policy and general scientific outreach.

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