Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation
Author:   Annika B. Malmberg ,  Keith R. Bley
Publisher:   Birkhauser Verlag AG
Edition:   2005 ed.
ISBN:  

9783764370800


Pages:   249
Publication Date:   15 August 2005
Format:   Hardback
Availability:   In Print   Availability explained
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Turning up the Heat on Pain: TRPV1 Receptors in Pain and Inflammation


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Overview

Vanilloids mediate their effects by selective agonism of an ion channel, the vanilloid receptor 1 (TRPV1). TRPV1 is a ligand-gated, non-selective, cation channel preferentially expressed in small-diameter, primary afferent neurons, including nociceptive sensory nerves. In addition to be activated by capsaicin and related vanilloids, TRPV1 responds to heat and extracellular acidification, and will integrate simultaneous exposures to these stimuli. The aim of this book is to summarize recent insights in the role of TRPV1 in pain and inflammation, and to discuss how modulation of this receptor may lead to important advances in analgesic drug development. Insights into the prospects for the therapeutic potential of TRPV1 activation or inhibition, particularly in various painful or inflammatory conditions, are provided. The volume is written for basic scientists and clinicians interested in the mechanisms of pain, inflammation and the treatment of these conditions.

Full Product Details

Author:   Annika B. Malmberg ,  Keith R. Bley
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   2005 ed.
Dimensions:   Width: 17.10cm , Height: 1.90cm , Length: 23.70cm
Weight:   0.618kg
ISBN:  

9783764370800


ISBN 10:   3764370807
Pages:   249
Publication Date:   15 August 2005
Audience:   College/higher education ,  Professional and scholarly ,  Tertiary & Higher Education ,  Postgraduate, Research & Scholarly
Format:   Hardback
Publisher's Status:   Active
Availability:   In Print   Availability explained
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

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