Overview

Tumor vascularization is directly linked to tumor progression and metastasis. Tumor cells require both oxygen and nutrients to survive. Cancer growth beyond a certain size requires vascularization, which is brought on by a number of molecular mechanisms. Tumor vascularization is caused by a variety of biological processes that not only leads to different tumor types and anatomic location but they also take place concurrently inside the same cancer tissue. These processes are controlled by a variety of signaling pathways and secreted factors. It also involves the participation of non-endothelial cells, like progenitors or cancer stem cells. Vascular imaging approaches have been developed to detect tumor blood flow and perfusion. These approaches include arterial spin labeling, DCE MRI, contrast-enhanced PET, CT, and ultrasound imaging. This book aims to shed light on some of the unexplored aspects of tumor vascularization and the recent researches in this field. It includes a detailed explanation of the various diagnostic and therapeutic techniques associated with tumor vascularization. The extensive content of this book provides the readers with a thorough understanding of the condition.

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9781646466689

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