Overview

The urgent need for the development of early tumor diagnosis and effective anti-tumor therapies remains. This work intends to provide a relatively broad audience with a novel approach for the development of cancer diagnostics and targeted therapeutics, based on recently proved hypotheses. It provides coverage of the most important aspects of a selected domain of tumor immunology, namely the characteristics and potential capacity of the tumor infiltrating B lymphocytes.

Full Product Details

Author:   Beatrix Kotlan
Publisher:   Springer-Verlag New York Inc.
Imprint:   Springer-Verlag New York Inc.
Edition:   1st ed. 2020
ISBN:  

9780387698816

ISBN 10:   0387698817
Pages:   160
Publication Date:   July 2007
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Awaiting stock  
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Table of Contents

Chapter 1. Tumor infiltrating T lymphocytes: Brief summary about the characteristics and role of tumor infiltrating T lymphocytes. Chapter 2. Tumor infiltrating B lymphocytes: Characteristics, potential capacity and role of tumor infiltrating B lymphocytes. Chapter 3. B lymphocytes in different solid tumors: Melanomas, breast carcinomas, ovarian carcinomas, neuroblastoma Chapter 4. Results of immunoglobulin repertoire analysis: Fetal and adult normal B cells compared to B cells from tumor tissues. Chapter 5. Potential capacity of natural human antibodies for therapeutic approaches Chapter 6. Potential capacity of autoantibodies for therapeutic approaches Chapter 7. Potential capacity, benefits and drawbacks of different antibody fragments for therapeutic approaches Chapter 8. Methodological arsenal of antibody engineering and biotechnology for developing novel immunoconjugates for diagnostics and therapeutics. Chapter 9. The secret of tumor infiltrating lymphocytes: novel tumor-specific target antigens revealed. Chapter 10. The sleeping beauty might be awaked: A special family of tumor associated molecules, the gangliosides. Chapter 11. Achievements and future prospects for novel tumor diagnostics and therapeutics Chapter 12. The benefits of targeted therapeutics to defeat cancer.

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