Overview
There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance.
Full Product Details
Author: Dmitry I. Gabrilovich ,
Arthur Andrew Hurwitz
Publisher: Springer-Verlag New York Inc.
Imprint: Springer-Verlag New York Inc.
Edition: 1st ed. Softcover of orig. ed. 2008
Dimensions:
Width: 15.50cm
, Height: 1.60cm
, Length: 23.50cm
Weight: 0.480kg
ISBN: 9781441924001
ISBN 10: 1441924000
Pages: 302
Publication Date: 29 October 2010
Audience:
Professional and scholarly
,
Professional & Vocational
Replaced By: 9781489980557
Format: Paperback
Publisher's Status: Active
Availability: In Print
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Reviews
From the reviews: The overall goal of this book is to describe what is currently known about the ways tumors circumvent destruction by the host's immune system. ... The book is targeted at researchers -- immunologists in general and, more specifically, tumor immunologists. It also provides a good source of information for graduate students and postdoctoral fellows. The editors of the book and the authors of the chapters are authorities in the areas they discuss. ... a useful addition to the field. (Marion C. Cohen, Doody's Review Service, August, 2008)
From the reviews: The overall goal of this book is to describe what is currently known about the ways tumors circumvent destruction by the host's immune system. ! The book is targeted at researchers -- immunologists in general and, more specifically, tumor immunologists. It also provides a good source of information for graduate students and postdoctoral fellows. The editors of the book and the authors of the chapters are authorities in the areas they discuss. ! a useful addition to the field. (Marion C. Cohen, Doody's Review Service, August, 2008)
From the reviews: The overall goal of this book is to describe what is currently known about the ways tumors circumvent destruction by the host's immune system. ... The book is targeted at researchers -- immunologists in general and, more specifically, tumor immunologists. It also provides a good source of information for graduate students and postdoctoral fellows. The editors of the book and the authors of the chapters are authorities in the areas they discuss. ... a useful addition to the field. (Marion C. Cohen, Doody's Review Service, August, 2008)
