Overview

Basic science and clinical pain research is particularly challenging for several reasons. First, pain is a subjective experience in response to nociception that follows actual or potential tissue damage. Since the ability to respond to this warning signal is essential for our survival, the nociceptive system that produces and transmits nociceptive signals is remarkably redundant and involves diffuse regions of the central nervous system. Second, unlike other sensory modalities, pain is a multi-dimensional experience including at least cognitive, affective, and sensory-discriminative components. Third, pain experiences can be influenced by psychological, socioeconomic, cultural, and genetic predispositions, making it exceedingly complicated to study pain and pain modulation. In this first volume, the current status and new trends of pain research are selectively discussed in order to take a critical and constructive look at the achievements of basic science research that have made significant differences in clinical pain management as well as the gaps between basic science research and clinical pain management.

Full Product Details

Author:   Jianren Mao
Publisher:   Nova Science Publishers Inc
Imprint:   Nova Science Publishers Inc
Dimensions:   Width: 26.00cm , Height: 3.60cm , Length: 18.00cm
Weight:   1.192kg
ISBN:  

9781600212062

ISBN 10:   1600212069
Pages:   476
Publication Date:   01 June 2006
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   Active
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Preface; Theories of Pain; Spinal Cord Mechanisms of Pain and their Modulation; Long-Lasting Sensory Potentiation: A Synaptic Model for Central Pain; Molecular Pain and Pain Management; A Dual-System Integration Model of Pain Mechanisms: Implications for Clinical Pain; Animal 'Pain' Models and Behavioural Tests in Pre-clinical Studies; Pain Assessment Tools used in Clinical Pain Management: Implications for Translational Research; Experimental Pain Testing: Measurement and Clinical Relevance; In Silico Genetic Analysis of Pain and Analgesia Related Traits; Sex Differences in Pain: Translational Challenges and Opportunities; Placebo Effects and Meaning Response: Perspectives from Consciousness Studies; Preclinical Studies of Intrathecal Analgesics; Intrathecal Drug Delivery for Chronic Pain Management; Spinal Cord Stimulation: Mechanisms and Clinical Application; Drug Delivery Methods; Index.

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