Overview

Toxoplasma gondii, once an obscure protozoan parasite, has recently become the focus of intense research, both as a serious pathogen in its own right and as a model member of the phylum Apicomplexa. Written by internationally acclaimed researchers, this is the first book to provide a comprehensive coverage of this important parasite from both the host and pathogen perspectives. The authors of this book describe in detail the biological characteristics that make T. gondii and related apicomplexans the most common and successful group of parasites on earth. Essential reading for all researchers working with Toxoplasma and related apicomplexans, Plasmodium, Cryptosporidium, and other protozoan parasites.

Full Product Details

Author:   James W. Ajioka (Cambridge University, UK) ,  Dominique Soldati (University of Geneva, Switzerland)
Publisher:   Taylor & Francis Ltd
Imprint:   Horizon
Dimensions:   Width: 15.60cm , Height: 4.00cm , Length: 23.40cm
Weight:   1.315kg
ISBN:  

9781904933342

ISBN 10:   1904933343
Pages:   650
Publication Date:   26 July 2007
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Hardback
Publisher's Status:   No Longer Our Product
Availability:   Out of stock  
The supplier is temporarily out of stock of this item. It will be ordered for you on backorder and shipped when it becomes available.

Table of Contents

Part 1: Overview 1. The Life Cycle of Toxoplasma gondii 2. Ultrastructure Part 2: Pathogenesis, Immunology and Virulence 3. Epidemiology, Diagnostics and Chemotherapy 4. Ocular Toxoplasmosis: Clinical Features, Pathology, Pathogenesis, Animal Models and Immune Responses 5. Congenetial Toxoplasmosis 6. Innate Recognition and the Regulation of Protective Immunity to Toxoplasma gondii 7. Mechanisms of Immune Evasion 8. Apoptosis and its Impact on the Parasite-Host Interaction 9. Pathogenicity and Virulence in Toxoplasma gondii 10. Cellular Response to Infection Part 3: Genome and Genetics 11. Genetics and Genome Organization of Toxoplasma gondii 12. Evolution and Comparative Genomics of Toxoplasma gondii 13. Population Genetics, Sex and the Emergence of Clonal Lines of Toxoplasma gondii 14. Manipulating the Toxoplasma Genome Part 4: Growth, Development and Metabolism 15. Cell Cycle Control/Parasite Division 16. Toxoplasma Gene Regulation and Bradyzoite Development 17. Biology of Bradyzoites 18. Chromatin Remodeling 19. Lipid Synthesis and Uptake 20. Nucleotides and Amino Acids Part 5: Organelles: Sorting, Content and Function 21. Protein Targeting to the Apicoplast 22. The Metabolic Functions of the Mitochondrion and the Apicoplast 23. Microneme Protein Repertoire and Function 24. Proteomic Analysis of the Rhoptry Organelles of Toxoplasma gondii 25. Dense Granules of the Infectious Stages of Toxoplasma gondii: Their Central Role in the Host/Parasite Relationship 26. Calcium Homeostasis and Acidcalciosomes in Toxoplasma gondiiPart 6: Cytoskeleton, Signaling, Motility and Invasion 27. Tubulin, Microtubules and Microtubule-Associated Structures in Toxoplasma gondii 28. Molecular Motors 29. Actin Dynamics and Motility in Apicomplexans 30. Proteases of Toxoplasma gondii 31. The Toxoplasma gondii Parasitophorous Vacuole Membrane: Transactions at the Parasite Host Interface

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James W. Ajioka, Dominique Soldati

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