Toxoplasma Gondii: The Model Apicomplexan Perspectives and Methods

Author:   Louis M. Weiss (Professor of Medicine and Pathology, Albert Einstein College of Medicine of Yeshiva University, NY, USA) ,  Kami Kim (Professor of Internal Medicine (Infectious Diseases and International Medicine) and Professor of Global Health, University of South Florida, USF Medicine International, Tampa, Florida)
Publisher:   Elsevier Science Publishing Co Inc
Edition:   3rd edition
ISBN:  

9780128150412


Pages:   1242
Publication Date:   20 March 2020
Replaced By:   9780443450488
Format:   Hardback
Availability:   Available To Order   Availability explained
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Toxoplasma Gondii: The Model Apicomplexan Perspectives and Methods


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Overview

Toxoplasma gondii: The Model Apicomplexan - Perspectives and Methods, Third Edition, reflects significant advances in the field in the last five years, including new information on the genomics, epigenomics and proteomics of T. gondii, along with a new understanding of the population biology and genetic diversity of this organism. This edition expands information on the effects of T. gondii on human psychiatric disease and new molecular techniques, such as CAS9/CSPR. T gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists.

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Author:   Louis M. Weiss (Professor of Medicine and Pathology, Albert Einstein College of Medicine of Yeshiva University, NY, USA) ,  Kami Kim (Professor of Internal Medicine (Infectious Diseases and International Medicine) and Professor of Global Health, University of South Florida, USF Medicine International, Tampa, Florida)
Publisher:   Elsevier Science Publishing Co Inc
Imprint:   Academic Press Inc
Edition:   3rd edition
Weight:   2.650kg
ISBN:  

9780128150412


ISBN 10:   0128150416
Pages:   1242
Publication Date:   20 March 2020
Audience:   Professional and scholarly ,  Professional & Vocational
Replaced By:   9780443450488
Format:   Hardback
Publisher's Status:   Active
Availability:   Available To Order   Availability explained
We have confirmation that this item is in stock with the supplier. It will be ordered in for you and dispatched immediately.

Table of Contents

1. The History and Life Cycle of Toxoplasma gondii 2. The Ultrastructure of Toxoplasma gondii 3. Molecular Epidemiology and Population Structure of Toxoplasma gondii 4. Human Toxoplasma Infection 5. Ocular Disease due to Toxoplasma gondii 6. Toxoplasmosis in Wild and Domestic Animals 7. Toxoplasma Animal Models and Therapeutics 8. Biochemistry and Metabolism of Toxoplasma gondii: Lipids and Nutrient Acquisition 9. Biochemistry and Metabolism of Toxoplasma gondii: Nucleotide and Amino Acid Metabolism 10. Biochemistry and Metabolism of Toxoplasma gondii: Carbohydrates and Metabolomics 11. The Apicoplast and Mitochondrion of Toxoplasma gondii 12. Calcium Storage and Homeostasis in Toxoplasma gondii 13. Signaling Networks in Toxoplasma gondii 14. Toxoplasma Secretory Proteins (Micronemes, Rhoptries, Dense Granules) 15. Toxoplasma Secretory Pathway, Intracellular Trafficking, and Autophagy 16. The Toxoplasma Cytoskeleton: Structures, Proteins and Processes (Need to include actin) 17. Toxoplasma Host Effectors in Cell Interactions 18. Bradyzoite and Sexual Stage Development 19. Development and Application of Classical Genetics in Toxoplasma gondii 20. Genetic Manipulation of Toxoplasma gondii 21. Epigenetic and Genetic Factors that Regulate Gene Expression in Toxoplasma gondii 22. Proteomics and Post Translational Protein Modifications in Toxoplasma gondii 23. ToxoDB: An Integrated Functional Genomic Resource for Toxoplasma and Other Sarcocystidae 24. Cerebral Toxoplasmosis: Pathogenesis, Host Resistance and Behavioral Consequences 25. Innate Immunity to Toxoplasma gondii 26. Adaptive Immunity and Genetics of the Host Immune Response

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Author Information

Louis M. Weiss, MD, MPH is Professor of Medicine (Division of Infectious Diseases) and Professor of Pathology (Division of Parasitology and Tropical Medicine) of the Albert Einstein College of Medicine, Bronx, New York. Dr. Weiss received his M.D. and M.P.H degrees from the Johns Hopkins University in 1982. He then completed a residency in Internal Medicine at the University of Chicago and a fellowship in Infectious Diseases at the Albert Einstein College of Medicine. Following this fellowship, he joined the faculty at Einstein where he is currently a Professor of Pathology and Medicine. His laboratory group has an active research program on parasitic diseases with a research focus on Toxoplasma gondii, the Microsporidia and Trypanosoma cruzi. Dr. Weiss is the author of over 200 publications and the editor of 3 books on parasitology. He is a fellow of the American College of Physicians, Infectious Disease Society of America and the American Academy of Microbiology. Dr. Weiss is the Co-Director of the Einstein Global Health Center. Dr. Kami Kim is a physician-scientist who joined the USF faculty in 2017 as a Professor of Internal Medicine (Infectious Diseases and International Medicine) and Professor of Global Health. Her laboratory focuses upon understanding the pathogenesis of toxoplasmosis and malaria, parasitic diseases of global significance. The Toxoplasma projects use a multidisciplinary systems biology approach to understand how the parasite senses and responds to changes in its host. Using a combination of epigenomics, genetics and proteomics, her group is studying how the parasite transitions from the pathogenic tachyzoite form to the persistent bradyzoite form. She is investigating the epigenetic and genetic factors that govern the host response to parasites. Dr. Kim is a fellow of the American Academy of Microbiology and the Infectious Disease Society of America as well as an elected member of the Association for American Physicians and the American Society for Clinical Investigation.

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