Overview

This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding their toxicity to vertebrate organisms. This book includes chapters on human and wildlife exposure/body burdens, reviews of metabolism and toxicological effects by organ system/developmental stage and aspects of PFAS toxicity that are driving PFAS research and regulatory oversight. Toxicological Effects of Perfluoroalkyl and Polyfluoroalkyl Substances provide critical assessments of the most controversial topics surrounding toxicological evaluation of PFASs to give readers an expert perspective on the issues. Emphasis is placed on the integration of modes and mechanisms of action with functional endpoints that are relevant to human and wildlife health. This book will be a useful resource for toxicologists, environmental chemists, risk assessors and researchers with an interest in the class of compounds known as perfluoroalkyl and polyfluoroalkyl substances.

Full Product Details

Author:   Jamie C. DeWitt
Publisher:   Birkhauser Verlag AG
Imprint:   Birkhauser Verlag AG
Edition:   Softcover reprint of the original 1st ed. 2015
Weight:   8.596kg
ISBN:  

9783319379173

ISBN 10:   3319379178
Pages:   495
Publication Date:   06 October 2016
Audience:   Professional and scholarly ,  Professional & Vocational
Format:   Paperback
Publisher's Status:   Active
Availability:   In Print  
This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us.

Table of Contents

Perfluorinated compounds: An overview.- Analysis of PFASs in biological tissues and fluids.- PFASs in the general population.- PFAS Biomonitoring in Higher Exposed Populations.- Perfluorinated Alkyl Acids in Wildlife.- Metabolism and Pharmacokinetics.- Metabolic EffectsPFAS.- Developmental Toxicity.- Neurotoxicity.- Immunotoxicity of Perfluoroalkylated Compounds.- Effects of PFOA on Endocrine-related Systems.- Carcinogenicity of Perfluoroalkyl Compounds.- Epidemiological Findings.- Dosimetric Anchoring of Toxicological Studies.- Human Health Risk Assessment of Perfluoroalkyl Acids.- Systematic Review, An Illustration of Increased Transparency in a Framework for Evaluating Immunotoxicity Associated with PFOA and PFOS Exposure.- Toxicology data for alternative “short-chain” fluorinated substances.- Conclusions and recommendations.  

Reviews

Author Information

Tab Content 6

Author Website:  

Customer Reviews

Recent Reviews

No review item found!

Add your own review!

Countries Available

All regions