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OverviewOverall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention. Full Product DetailsAuthor: Stefan Bauer , Gunther HartmannPublisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG Imprint: Springer-Verlag Berlin and Heidelberg GmbH & Co. K Edition: 2008 ed. Volume: 183 Dimensions: Width: 15.50cm , Height: 1.50cm , Length: 23.50cm Weight: 0.553kg ISBN: 9783540721666ISBN 10: 3540721665 Pages: 240 Publication Date: 18 December 2007 Audience: Professional and scholarly , Professional & Vocational Format: Hardback Publisher's Status: Active Availability: In Print ![]() This item will be ordered in for you from one of our suppliers. Upon receipt, we will promptly dispatch it out to you. For in store availability, please contact us. Table of ContentsToll-Like Receptors (TLRs) and Their Ligands.- Signalling of Toll-Like Receptors.- TLR9-Mediated Recognition of DNA.- RNA Recognition via TLR7 and TLR8.- Fungal Recognition by TLR2 and Dectin-1.- Heat Shock Proteins and Toll-Like Receptors.- Nucleic Acid Recognition Receptors in Autoimmunity.- Dendritic Cell Subsets and Toll-Like Receptors.- Structure of Toll-Like Receptors.- Toll-Like Receptor-Agonists in the Treatment of Skin Cancer: History, Current Developments and Future Prospects.- Vaccination with Messenger RNA (mRNA).ReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |